Vanderbilt University School of Medicine, Medical Scientist
August, 2004 PhD in Pharmacology, with Lee E. Limbird, Ph D,
Vasopressin Receptor with Calmodulin: Mutations of the C-
terminus that Eliminate Calmodulin Binding also Eliminate AVP-
Assistant Professor, Division of Neuropathology, Vanderbilt University Medical Center.
Fellow, Division of Neuropathology, AP/NP Program, Vanderbilt University Medical Center.
Resident, Department of Anatomic Pathology, AP/NP Program Vanderbilt University Medical Center.
Research Assistant: Philip Stahl, PhD, Department of Cell Biology; Washington University in St. Louis, Role of Rab11 and Rab5 in endocytosis and intracellular trafficking.
Research Assistant: K. D. Moeller, Department of Chemistry; Washington University in St. Louis, Synthesis of conformationally-restricted thyrotropin releasing hormone peptidomimetics.
PUBLICATIONS Nickols HN, Chambless LB, Carson RB, Coffin C, Pearson MM, Abel TW. “Intramedullary spinal immature teratoma: Resolution of quadreiplegia following resection is a four-week-old infant.” Journal of Neurosurgery: Pediatrics, (in press). Mason WJ, Nickols HH. Images in Clinical Medicine. Crystalluria from acyclovir use. N Engl J Med. 2008 Mar 27; 358 (13): e14. Nickols HH, Shah VN, Chazin WJ, Limbird LE. "Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C-terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium." Journal of Biological Chemistry. 2004 279(45): 46969. Tan CM, Brady AE, Nickols HH, Wang Q, Limbird LE. "Membrane trafficking of G protein-coupled receptors." Annual Review of Pharmacology and Toxicology. 2004 44:559-609. Tan, CM‡, Nickols, HH‡, Limbird, LE. "Appropriate polarization following pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic diabetes insipidus alleles involves a conformation of the receptor that also attains mature glycosylation." Journal of Biological Chemistry. 2003 12; 278(37):35678. ( ‡ these two authors contributed equally to this work) Wilson, MH, Highfield, HA, Limbird LE. "The role of a conserved inter-transmembrane domain interface in regulating alpha 2a-adrenergic receptor conformational stability and cell-surface turnover." Molecular Pharmacology. 2001 59(4):929-38 Barbieri MA, Roberts RL, Gumusboga A, Highfield H, Alvarez-Dominguez C, Wells A, Stahl PD. "Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a." Journal of Cell Biology. 2000. 151(3):539-50. PRESENTATIONS
Gordon Research Conference, Molecular Pharmacology 2002,
Annual Meeting of the American Association of Neuropathologists 2009, Platform Presentation, “Autopsy Case of Campomelic Dysplasia and Subpial Neuronal Heterotopias: Potential Role of SOX9 in Cortical Neuronal Migration.” Hilary Nickols, Flavinia Nunes, Hernan Correa, Ty Abel
Annual Meeting of the American Association of Neuropathologists 2009, Poster Presentation, “The Neuropathology of Brown-Vialetto-Van Laere Syndrome: A Detailed Case Report.” Hilary Nickols, Julianne Qualtieri, Marcia Wills, Hannah Kinney, Mark Becher
Annual Meeting of the American Association of Neuropathologists 2009, Poster Presentation, “Group II metabotropic glutamate receptor allosteric agents as potential tools in the investigation and treatment of gliomas.” Hilary Highfield Nickols, Douglas J. Sheffler, Shyama Sidique, Dhanya Panickar, Russell Dahl, Li Yang, Ananda Herath, Robert Ardecky, Nicholas D. P. Cosford, P. Jeffrey Conn.
Annual Meeting of the American Association of Neurological Surgeons, Poster Presentation, "Resolution of quadriplegia following resection of an immature intramedullary teratoma in an infant." Lola Blackwell, Luke Tomycz, Hilary H. Nickols, Ty W. Abel, Matthew Pearson.
PROFESSIONAL SOCIETY MEMBERSHIPS College
American Association of Neuropathologists American Association of Investigative Pathologists
GRANTS AND ACADEMIC AWARDS 2008
John L. Shapiro Award for excellence in Pathology
SERVICE 2008-9, 2009-10 2003-4, 2004-5
Committee Member: MSTP Student Advisory Committee
Committee Member: MSTP Admissions Committee
Pharmacology Forum. Mark Pittinger, PhD, Perry Bartlett,
PhD, Ronald Green, PhD. “Stem Cell Research – The
Dr. Peter Burger, Department of Neuropathology, Johns Hopkins Medical Center, June 15-26, two week rotation in neuropathology
Dr. Hans Grossniklaus, Departments of Ophthomology and Pathology, Emory University Medical Center, August 17-24, one week rotation in ophthalmic pathology
Iranian J. Publ. Health, Vol. 30, Nos. 1-2, PP. 37-40, 2001 Iranian J. Publ. Health, Vol. 30, Nos. 1-2, PP. 37-40, 2001 Sister Chromatid Exchanges and Micronuclei in Lymphocyte of Nurses Handling Antineoplastic Drugs ∗ M Ansari-Lari 1 , M Saadat 2 , M Shahryari 3 , DD Farhud 4 1 Dept. of Social Medicine school of Medicine, Shiraz University of Medical Sciences, Ira
WISSENSCHAFT Publication Sleep bruxism and sleep-disordered breathing in pediatrics: an overview for clinicians Schlaf-Bruxismus und schlafbezogene Atmungsstörungen in der Pädiatrie: eine Übersicht für Behandler 1 Dr. Maria Clotilde Carra, Zahnmedizinische Fakultät, 1 Dr. Maria Clotilde Carra, Faculty of Dentistry, 2 Nelly Huynh, PhD, Zahnmedizinische Fakultät, 2 Nelly Huyn