Hilary highfield nickols, m

Hilary Highfield Nickols, MD, PhD

EDUCATION

1998-2006
Vanderbilt University School of Medicine, Medical Scientist August, 2004 PhD in Pharmacology, with Lee E. Limbird, Ph D, Vasopressin Receptor with Calmodulin: Mutations of the C- terminus that Eliminate Calmodulin Binding also Eliminate AVP-
1993-1997

ACADEMIC CAREER

2010-Present
Assistant Professor, Division of Neuropathology, Vanderbilt University Medical Center.
2008- 2010
Fellow, Division of Neuropathology, AP/NP Program, Vanderbilt University Medical Center.
2006-2008
Resident, Department of Anatomic Pathology, AP/NP Program Vanderbilt University Medical Center.
1997-1998
Research Assistant: Philip Stahl, PhD, Department of Cell Biology; Washington University in St. Louis, Role of Rab11 and Rab5 in endocytosis and intracellular trafficking.
1996-1997
Research Assistant: K. D. Moeller, Department of Chemistry; Washington University in St. Louis, Synthesis of conformationally-restricted thyrotropin releasing hormone peptidomimetics.
PUBLICATIONS
Nickols HN, Chambless LB, Carson RB, Coffin C, Pearson MM, Abel TW.
“Intramedullary spinal immature teratoma: Resolution of quadreiplegia following
resection is a four-week-old infant.” Journal of Neurosurgery: Pediatrics, (in press).
Mason WJ, Nickols HH. Images in Clinical Medicine. Crystalluria from acyclovir use.
N Engl J Med. 2008 Mar 27; 358 (13): e14.
Nickols HH, Shah VN, Chazin WJ, Limbird LE. "Calmodulin interacts with the V2
vasopressin receptor: elimination of binding to the C-terminus also eliminates arginine
vasopressin-stimulated elevation of intracellular calcium." Journal of Biological
Chemistry. 2004 279(45): 46969.
Tan CM, Brady AE, Nickols HH, Wang Q, Limbird LE. "Membrane trafficking of G
protein-coupled receptors." Annual Review of Pharmacology and Toxicology. 2004
44:559-609.
Tan, CM‡, Nickols, HH‡, Limbird, LE. "Appropriate polarization following
pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic
diabetes insipidus alleles involves a conformation of the receptor that also attains mature
glycosylation." Journal of Biological Chemistry. 2003 12; 278(37):35678. ( ‡ these two
authors contributed equally to this work)
Wilson, MH, Highfield, HA, Limbird LE. "The role of a conserved inter-transmembrane
domain interface in regulating alpha 2a-adrenergic receptor conformational stability and
cell-surface turnover." Molecular Pharmacology. 2001 59(4):929-38
Barbieri MA, Roberts RL, Gumusboga A, Highfield H, Alvarez-Dominguez C, Wells A,
Stahl PD. "Epidermal growth factor and membrane trafficking. EGF receptor activation
of endocytosis requires Rab5a." Journal of Cell Biology. 2000. 151(3):539-50.

PRESENTATIONS

2002
Gordon Research Conference, Molecular Pharmacology 2002, Annual Meeting of the American Association of Neuropathologists 2009, Platform Presentation, “Autopsy Case of Campomelic Dysplasia and Subpial Neuronal Heterotopias: Potential Role of SOX9 in Cortical Neuronal Migration.” Hilary Nickols, Flavinia Nunes, Hernan Correa, Ty Abel Annual Meeting of the American Association of Neuropathologists 2009, Poster Presentation, “The Neuropathology of Brown-Vialetto-Van Laere Syndrome: A Detailed Case Report.” Hilary Nickols, Julianne Qualtieri, Marcia Wills, Hannah Kinney, Mark Becher Annual Meeting of the American Association of Neuropathologists 2009, Poster Presentation, “Group II metabotropic glutamate receptor allosteric agents as potential tools in the investigation and treatment of gliomas.” Hilary Highfield Nickols, Douglas J. Sheffler, Shyama Sidique, Dhanya Panickar, Russell Dahl, Li Yang, Ananda Herath, Robert Ardecky, Nicholas D. P. Cosford, P. Jeffrey Conn. Annual Meeting of the American Association of Neurological Surgeons, Poster Presentation, "Resolution of quadriplegia following resection of an immature intramedullary teratoma in an infant." Lola Blackwell, Luke Tomycz, Hilary H. Nickols, Ty W. Abel, Matthew Pearson.
PROFESSIONAL SOCIETY MEMBERSHIPS
College
American Association of Neuropathologists American Association of Investigative Pathologists
GRANTS AND ACADEMIC AWARDS
2008
John L. Shapiro Award for excellence in Pathology 1993-1997

SERVICE
2008-9, 2009-10
2003-4, 2004-5
Committee Member: MSTP Student Advisory Committee 2001-2, 2002-3
Committee Member: MSTP Admissions Committee Pharmacology Forum. Mark Pittinger, PhD, Perry Bartlett, PhD, Ronald Green, PhD. “Stem Cell Research – The
EDUCATIONAL ACTIVITIES

2009
Dr. Peter Burger, Department of Neuropathology, Johns Hopkins Medical Center, June 15-26, two week rotation in neuropathology Dr. Hans Grossniklaus, Departments of Ophthomology and Pathology, Emory University Medical Center, August 17-24, one week rotation in ophthalmic pathology

Source: http://www.connlab.com/Lab%20Members/NickolsH_CV_2010-9-30.pdf