Newsletter, Volume 2, Number 7 – July 2010

In the News
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Curcuma domestica vs NSAIDs for Knee Osteoarthritis In 2009, a human trial (107 subjects) compared the effects of turmeric (Curcuma domestica) versus a non-steroidal anti-inflammatory drug (NSAID) for osteoarthritis of the knee. This randomized controlled study examined the safety profile and clinical efficacy of Curcuma domestica extracts for pain reduction and overall functional improvement in subjects with knee osteoarthritis. Subjects with a pain score of >= 5 were given either 800mg/day of ibuprofen or 2000mg of turmeric extracts for 6 weeks. The end points of the study were reduction in pain upon walking, pain climbing stairs, and knee function assessed by subjects walking up and down stairs. Results of the study showed no difference in pain and functional outcomes for both the NSAID and turmeric groups;
there were also no significant difference in the adverse events between the groups; as such the authors reported that
Curcuma domestica as being comparable in safety and efficacy to ibuprofen for the management of osteoarthritis of
the knee (J Altern Complement Med. 2009 Aug;15(8):891-7.
Naturopathic Options:
While the aforementioned study reported no difference in the adverse events for either NSAID or turmeric, I would
advise for subjects with a previous history of peptic or duodenal ulcer to avoid the former in consideration of the risk
of gastrointestinal bleeding and ulceration. Secondly, the intake of NSAID with alcohol increases one’s risk for liver
toxicity, of course, depending on the amount of NSAID and alcohol consumed.
While turmeric is a great alternative for its anti-inflammatory effects, the herb is also used clinically to support the
liver’s detoxification processes (it may alter metabolism of certain prescription drugs); additionally, it is a potent anti-
oxidant as well as a blood thinner secondary to its antiplatelet aggregating activity (* Caution for those on Warfarin or
Aspirin). Used in Asian and Middle Eastern cooking, this spice has been found to be useful in traditional medicine for
relieving symptoms of irritable bowel syndrome and ulcerative colitis. Preclinical studies also indicate curcumin (the
active ingredient in turmeric) has potent chemoprotective actions against a variety of tumors.
Advice from Dr. Aaron Hoo
If you or someone you know has been diagnosed with osteoarthritis, it would be prudent to ensure that the joint is
supported so as to delay the progression of the condition. Avoidance of known food allergens/sensitivities is prudent
so as to reduce the risk for low grade systemic inflammation. Secondly, cartilaginous support such as glucosamine
(*Caution if allergic to shellfish) and chondroitin sulfate may be a good adjunctive therapy to turmeric’s anti-
inflammatory actions, however, some may also complain of a mild gastro-intestinal upset with glucosamine sulfate.
As always, drinking plenty of water, getting lots of rest and minimizing your stress is a great way to naturally reduce
the inflammatory process percolating in your body. Otherwise, consider checking out my online store:, log in with your username and password and look for the
following products: Chondrocare, Collagenics, Kaprex & UltraInflamX.

Dr. Aaron Hoo,
Doctors’ Choice Nutrition
1190 Thurlow Street Vancouver, BC V6E 1X3 MUSHROOM TOMATO SOUP (6 cups) – Gluten Free
½ yellow onion; 1 cup (1/3 pound) button or cremini mushrooms; 3 tbsp vegetable oil; 3 tbsp sorghum flour; 1 clove garlic; 4 cups vegetable broth; 2 x 6 oz. cans tomato paste; 1 cup plain soy milk; 1 tsp dried basil; ½ tsp sea salt. Dice onions and slice mushrooms. Put the oil & flour in saucepan over medium heat and stir continuously for 5 minutes. Add garlic, onion & mushroom and stir frequently. If it’s cooking too fast, add a little broth to the pan (1/2 cup). Saute for 5 minutes. Add about 2 cups of vegetable broth, then add tomato paste. Stir until the paste becomes completely smooth. Add the rest of the broth, the soy milk, basil and salt. Stir well and heat through.
Clinic Savings

Bring this portion into the clinic to receive
your next supplement purchase
**This offer is not to be used with any other discounts or in-store promotions. Offer applicable once per month per household**
Dr. Aaron Hoo,
Doctors’ Choice Nutrition
1190 Thurlow Street Vancouver, BC V6E 1X3


Reg area studenti vecchio ordinamento

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Annals of Oncology 21 (Supplement 7): vii270–vii276, 2010Histology-driven chemotherapy of soft-tissue sarcomaDepartment of Oncology, Lund University and Ska˚nes University Hospital, Lund, SwedenSoft-tissue sarcomas are rare diseases with >50 subtypes. Surgery is the most important treatment in localizeddisease, sometimes combined with radiotherapy. Chemotherapy is used as palliation in a

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