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Thursday, Dec. 9, 2004, 11 a.m. EST Susan Herold, 202-462-6262
Over-the-Counter Drug as Likely to Relieve Heartburn, Reflux as Prescriptions Costing $2,400 a Year Prilosec OTC Chosen as Consumer Reports Best Buy Drug
(Washington, D.C.) – People who take prescription drugs for heartburn, ulcers or acid-reflux disease could save more than $200 a month by considering over-the-counter Prilosec, the Consumer Reports Best Buy Drug in the category know as proton pump inhibitors (PPIs). A Consumers Union comparison of PPIs released today indicates that nonprescription Prilosec OTC (omeprazole) is just as likely as prescription PPIs to relieve heartburn and ulcers, and promote healing for most people with gastroesophageal reflux disease, at a savings of up to $2,400 a year. Prilosec OTC costs about 79 cents a day, while prescription PPIs can range up to $8 a day. The Consumers Union analysis found it as effective as the more expensive alternatives for most people. “Some of the proton pump inhibitors are widely advertised and quite costly, and many doctors believe they may be overused,” said Gail Shearer, director of health policy analysis for Consumers Union. “We urge people to check with their doctor to determine if they really need one of these medicines, and to consider the non-prescription drug, particularly if they have no health insurance or prescription drug coverage,” Shearer added. The analysis recommends that people with drug coverage check to see if their insurer provides a discount coupon for Prilosec OTC. If not, they should talk with their doctor about choosing the PPI that has the lowest out-of-pocket cost under their insurance plan. Consumer Reports Best Buy Drugs is an educational and outreach initiative that will compare a variety of prescription drugs on price, effectiveness and safety to help consumers and their doctors identify the most effective and affordable medicines. Consumers can download reports from the free website, , of the first three drug categories reviewed: cholesterol-lowering statins, PPIs, and arthritis and pain medicines. Each month, CRBestBuyDrugs.org will feature a report on another drug category. Consumer Reports Best Buy Drugs combines evidence-based research on the comparative effectiveness and safety of prescription drugs with national-level data on drug prices. The information on drug effectiveness is derived from the Drug Effectiveness Review Project (DERP)
and price information based on average retail prices paid in cash by consumers at the pharmacy. The CU reports are peer-reviewed by medical experts in the particular drug category.
Comparative Effectiveness of PPIs1 Complete Esophageal Generic Name Brand Name Healing at 8 Prevention with dose per day Relief (% of patients) patients) patients)
1. Effectiveness data presented for those PPI dosage strengths that have been studied to date PPI Price Comparison Generic Name with dose per day Brand Name1
Lansoprazole 15mg delayed release lingual tablets
Lansoprazole 30 mg delayed release lingual tablets Prevacid
Lansoprazole 15mg sustained release tablets
Lansoprazole, 30 mg sustained release tablets
Lansoprazole 30mg enteric coated capsules
Lansoprazole 15mg delayed release suspension packets
Lanzoprazole 30 mg delayed release suspension packets
9Omeprazole 20 mg Prilosec OTC3
Omeprazole 10mg sustained release capsules
Omeprazole 20mg sustained release capsules
Omeprazole 40mg sustained release capsules
Omeprazole 10mg sustained release capsules
Omeprazole 20mg sustained release capsules
1. “Generic” indicates drug sold by generic name, omeprazole 2. Prices reflect nationwide retail average for September 2004, rounded to nearest dollar; data provided by NDCHealth, a healthcare information company. 3. This is a non-prescription (over-the-counter) version of omeprazole available at any drug store. Consumer Reports Best Buy Drugs is funded in part with a major grant from the Engelberg Foundation, a charitable trust that supports a wide range of activities in the fields of health care, science and education. The project is also partially funded through a grant from the National Library of Medicine of the National Institutes of Health. (c) Consumers Union 2004. The material above is intended for legitimate news entities only; it may not be used for commercial or promotional purposes. Consumers Union, the publisher of Consumer Reports®, is an expert, independent nonprofit organization whose mission is to work for a fair, just, and safe marketplace for all consumers and to empower consumers to protect themselves. To achieve this mission, we test, inform, and protect. To maintain our independence and impartiality, CU accepts no outside advertising, no free test samples, and has no agenda other than the interests of consumers. CU supports itself through the sale of our information products and services, individual contributions, and a few noncommercial grants.
Articles Medical therapy to facilitate urinary stone passage: a meta-analysis John M Hollingsworth, Mary A M Rogers, Samuel R Kaufman, Timothy J Bradford, Sanjay Saint, John T Wei, Brent K Hollenbeck Summary Background Medical therapies to ease urinary-stone passage have been reported, but are not generally used. If eff ective, Lancet 2006; 368: 1171–79 such therapies would incr