Material Safety Data Sheet 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THE COMPANY/UNDERTAKING Product Name Catalog No. Recommended Use Recommended Use
antibiotic/antimycotic for cell culture, blocks the binding of tRNA to the 30S subunit
Synonyms
ACHROMYCIN HYDROCHLORIDE * ALA TET * AMYCIN, HYDROCHLORIDE
*ARTOMYCIN * BRISTACYCLINE * CANCYCLINE-250 * CEFRACYCLINE
TABLETS *CHLORHYDRATE DE TETRACYCLINE (FRENCH) *
CHLOROWODORKU TETRACYKLINY (POLISH) * CYCLOPAR * DIACYCINE *
DUMOCYCLIN * HOSTACYCLINE *MEDAMYCIN * MEPHACYCLIN *
NCI-C55561 * NEOCYCLINE B * PALTET * PANMYCIN HYDROCHLORIDE *
PARTREX * PIRACAPS * POLYCYCLINE HYDROCHLORIDE * POLYOTIC
OINTMENT * QIDTET * QUADRACYCLINE * QUATREX * REMICYCLIN *
RICYCLINE * RO-CYCLINE * SANCLOMYCINE * SANCLOMYCINE * STECLIN
* STILCICLINA * SUBAMYCIN * SUMYCIN * SUPRAMYCIN * TEFILIN * TELINE
* TELOTREX * TET-CY * TETRABAKAT * TETRABID * TETRABLET
*TETRACAPS * TETRACHEL * TETRACICLINA CLORIDRATO (ITALIAN) *
TETRACOMPREN * TETRACYCLINE CHLOROHYDRATE *
TETRACYCLINEHYDROCHLORIDE * TETRA-D * TETRAKAP * TETRALUTION *
TETRAMAVAN * TETRA-WEDEL * TETROSOL * TOPICYCLINE *
TRIPHACYCLIN * U-5965 * UNICIN *UNIMYCIN * VETQUAMYCIN-324 *
Emergency Telephone Number 519-590-7717 Company Phone Number E-mail Address 2. HAZARDS IDENTIFICATION GHS - Classification Classification
Skin Irritant 2 Eye Irritant 2 Germ Cell Mutagenicity 1B Toxic to Reproduction 1B
Respiratory Sensitizer 1 Skin Sensitizer 1 Acute Toxicity Oral 3
Signal Word Catalog No. Tetracycline Hydrochloride Hazard Statements
H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May
cause respiratory irritation H340 - May cause genetic defects H317 - May cause
an al ergic skin reaction H334 - May cause al ergy or asthma symptoms or
breathing difficulties if inhaled H301 - Toxic if swallowed
Precautionary Statements
P264 - Wash hands thoroughly after handling P280 - Wear protective
gloves/protective clothing/eye protection/face protection P201 - Obtain special
instructions before use P202 - Do not handle until all safety precautions have been
read and understood P271 - Use only outdoors or in a well-ventilated area P262 -
Do not get in eyes, on skin, or on clothing P270 - Do not eat, drink or smoke when
3. COMPOSITION/INFORMATION ON INGREDIENTS Chemical Name REACH Reg. No. Classification 4. FIRST AID MEASURES Eye Contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a
Skin Contact
Wash off immediately with soap and plenty of water removing all contaminated
Inhalation
Move to fresh air. If breathing becomes difficult, give oxygen
Ingestion
Clean mouth with water and afterwards drink plenty of water
Notes to Physician 5. FIRE-FIGHTING MEASURES Flammable Properties Flash Point Suitable Extinguishing Media
Use extinguishing measures that are appropriate to local
circumstances and the surrounding environment. Hazardous Combustion Products
Carbon oxides, Nitrogen oxides (NOx), Hydrogen Chloride gas. Catalog No. Tetracycline Hydrochloride Explosion Data Sensitivity to Mechanical Impact Sensitivity to Static Discharge Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus
pressure-demand, MSHA/NIOSH (approved or equivalent) and
6. ACCIDENTAL RELEASE MEASURES Personal Precautions
Avoid contact with skin, eyes and clothing. Use personal protective equipment. Ensure
Methods for Containment
Prevent further leakage or spil age if safe to do so
Methods for Cleaning Up
Avoid dust formation. Pick up and transfer to properly labeled containers. Ventilate area
and wash spil site after material pickup is complete. 7. HANDLING AND STORAGE Handling
Handle in accordance with good industrial hygiene and safety practice. Light
Keep containers tightly closed in a dry, cool and wel -ventilated place. Protect
Incompatible Products 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Chemical Name ACGIH TLV NIOSH IDLH Engineering Measures Personal Protective Equipment Eye/Face Protection Skin and Body Protection Respiratory Protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved
respiratory protection should be worn. Positive-pressure supplied air respirators may be
required for high airborne contaminant concentrations. Respiratory protection must be
provided in accordance with current local regulations
Hygiene Measures
Handle in accordance with good industrial hygiene and safety practice
Catalog No. Tetracycline Hydrochloride 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Odor Threshold Decomposition Temperature °C No information available Freezing Point Initial Boiling Point Physical State Flash Point Autoignition Temperature Boiling Point/Range Melting Point/Range Flammability Limits in Air Upper No data available Lower No data available Explosive Properties Oxidizing Properties Evaporation Rate MMHG @ 37.8 C Vapor Density Specific Gravity Solubility Partition Coefficient (n-octanol/water) Viscosity 10. STABILITY AND REACTIVITY Stability
Stable under recommended storage conditions
Incompatible Products Conditions to Avoid Hazardous Decomposition Products Carbon oxides. Nitrogen oxides (NOx). Hydrogen chloride gas. Hazardous Polymerization 11. TOXICOLOGICAL INFORMATION Acute Toxicity Product Information
Toxic by inhalation and if swal owed. Causes skin, eye and respiratory tract irritation. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation Chronic Toxicity Chronic Toxicity Catalog No. Tetracycline Hydrochloride Target Organ Effects 12. ECOLOGICAL INFORMATION Ecotoxicity
The environmental impact of this product has not been ful y investigated
13. DISPOSAL CONSIDERATIONS Waste Disposal Method
Dispose of material in accordance with al federal, state, and local regulations
Contaminated Packaging
Dispose of in accordance with all federal, state and local regulations
14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION REACH Title VII Restrictions Chemical Name Dangerous Pol ution Pol ution Poison and Substances Solvents Substances Release and Release and Deleterious Whose Names Transfer Transfer Substances Registry (Class Registry (Class Control Law: Indicated on the Label Component ISHA - Harmful ISHA - Harmful Toxic Chemical Toxic Release Toxic Release Substances Substances Classification Inventory (TRI) - Inventory (TRI) - Prohibited for Requiring Listing (TCCL) - Manufacturing, Permission Toxic Chemicals Importing, Transferring, or Supplying Catalog No. Tetracycline Hydrochloride International Inventories EINECS/ELINCS U.S. Federal Regulations
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemical
or chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372
Chemical Name SARA 313 - Threshold SARA 311/312 Hazard Categories Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Clean Water Act
This product does not contain any substances regulated as pol utants pursuant to the Clean Water Act (40 CFR 122.21 and 40
Clean Air Act, Section 112 Hazardous Air Pol utants (HAPs) (see 40 CFR 61)
This product does not contain any substances regulated as hazardous air pol utants (HAPS) under Section 112 of the Clean Air Act
U.S. State Regulations California Proposition 65
This product contains the fol owing Proposition 65 chemicals
Chemical Name California Prop. 65 International Regulations Mexico - Grade Catalog No. Tetracycline Hydrochloride WHMIS Hazard Class 16. OTHER INFORMATION Disclaimer The information provided on this MSDS is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of MSDS
MODULE 1 : Introduction to study of man Biochemistry – Undergraduate Programme Faculty of Medicine and Allied Sciences Rajarata University of Sri Lanka 1 Origin of Life Primordial Soup 1.1.1 Review the evidence that support evolution of life. 1.1.2 Recall the conditions that may have been present on the primitive earth favorable for the formation of biomolecules. 1.1.3 Des
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