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TAN Choon Hong
School of Physical & Mathematical Sciences Division of Chemistry and Biological Chemistry SPMS-CBC-04-18, 21 Nanyang Link, Singapore 637371
EDUCATION
1996 – 1999
PhD, University of Cambridge (Supervisor: Prof Andrew B. Holmes) B.Sc. (Hons), First Class, National University of Singapore
PROFESSIONAL EXPERIENCE
Apr 2012
Associate Professor, School of Physical & Mathematical Sciences Division of Chemistry and Biological Chemistry Associate Professor, Department of Chemistry National University of Singapore Dean’s Chair Professor (2011-2012) (Member, Faculty Tenure and Promotion Committee, 2011-2012) Distinguish Adjunct Professor Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province Henan University Kaifeng, Henan, P. R. China Assistant Professor, Department of Chemistry, National University of Singapore (Chair of Graduate Committee, Medicinal Chemistry Program, Office of Life Sciences, 2005-present; Member, Graduate Program in Bioengineering, Centre of Life Sciences, 2004-present; Member, Cardiovascular Program, Office of Life Sciences, 2005-2007) Department of Chemistry National Taiwan University Research Associate (Supervisor: Prof Robert R. Rando) Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Postdoctoral Fellow (Supervisor: Prof Yoshito Kishi) Department of Chemistry and Chemical Biology Harvard University
RESEARCH INTERESTS
• Synthetic Organic Chemistry
• Biological Chemistry
• Medicinal Chemistry

PUBLICATIONS
1.
C.H.Tan,
trifluoromethanesulfonate [Yb(OTf)3] promoted indium mediated allylation reactions of carbonyl-compounds in aqueous-media. Tetrahedron-Asymmetry, 1995, 6, 1825–1828. N.Srikanth, C.H.Tan, S.C.Ng, T.P.Loh, L.L.Koh and K.Y.Sim. Synthesis of heterocyclic
analogues of tamoxifen as potential antiestrogens. Journal of Chemical Research-S, 1997, 8, 274–
275; Journal of Chemical Research-M, 1997, 1828–1849.
W.P.Hems, C.H.Tan, T.Stork, N.Feeder and A.B.Holmes. Intramolecular cyclisation of (Z)-N-4-
alkenylnitrones and the effects of alkenyl substituents. Tetrahedron Letters, 1999, 40, 1393–1396.
C.H.Tan, T.Stork, N.Feeder and A.B.Holmes. Stereoselective synthesis of the indolizidine core
of the allopumiliotoxins. Tetrahedron Letters, 1999, 40, 1397–1400.
C.H.Tan and A.B.Holmes. Total synthesis of allopumiliotoxin 323B'. Chemistry-A European
Journal, 2001, 7, 1845–1854.
Y.Kobayashi, C.H.Tan and Y.Kishi. Toward creation of a universal NMR database for
stereochemical assignment: the case of 1,3,5-trisubstituted acyclic systems. Helvetica Chimica
Acta, 2000, 83, 2562–2571.
Y.Kobayashi, C.H.Tan and Y.Kishi. Stereochemical assignment of the C21-C38 portion of the
Desertomycin/Oasomycin class of natural products via universal NMR databases: Prediction.
Angewandte Chemie International Edition English, 2000, 39, 4279–4281.
C.H.Tan, Y.Kobayashi and Y.Kishi. Stereochemical assignment of the C21-C38 portion of the
Desertomycin/Oasomycin Class of natural products via universal NMR databases: Proof.
Angewandte Chemie International Edition English, 2000, 39, 4282–4284.
Y.Kobayashi, C.H.Tan and Y.Kishi. Toward creation of a universal NMR databases for
stereochemical assignment: Complete structure of the Desertomycin/Oasomycin class of natural
products, Journal of the American Chemical Society, 2001, 123, 2076–2078.

10. Y.Kobayashi, N.Hayashi, C.H.Tan and Y.Kishi. Toward the creation of NMR databases in chiral
solvents for assignments of relative and absolute stereochemistry: Proof of concept. Organic Letters, 2001, 3, 2245–2248.
11. D.H.Ryu, C.H.Tan and R.R.Rando. Synthesis of (+), (-)-Neamine and their positional isomers as
potential antibiotics. Bioorganic and Medicinal Chemistry Letters, 2003, 13, 901–903.
(2005)
12. W. Ye, J. Xu, C.T. Tan and C.H.Tan. 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) catalyzed
Michael reactions. Tetrahedron Letters, 2005, 46, 6875–6878.
(2006)
13. W. Ye, D. Leow, Serena L. M. Goh, C.-T. Tan, C.-H. Chian and C.-H. Tan. Chiral bicyclic
guanidines: a concise and efficient aziridine-based synthesis. Tetrahedron Letters, 2006, 47, 1007–1010.
14. J. Xu, Y. Guan, S. Yang, Y. Ng, G. Peh and C.-H. Tan, Chiral imidazoline promoted asymmetric
Baylis-Hillman reaction. Chemistry - An Asian Journal, 2006, 1, 724 – 729.
15. J. Shen, T. T. Nguyen, Y.-P. Goh, W. Ye, X. Fu, J. Xu and C.-H. Tan, Chiral bicyclic guanidine
catalyzed enantioselective reactions of anthrones. Journal of the American Chemical Society, 2006, 128, 13692–13693.
(2007)
16. Z. Jiang, Y. Zhang, W. Ye and C.-H. Tan, P-C Bond formation via direct and three-component
conjugate addition catalyzed by 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD). Tetrahedron Letters, 2007, 48, 51–54.
17. H. Liu and C.-H. Tan, Iodobenzene-catalysed iodolactonisation using sodium perborate
monohydrate as oxidant. Tetrahedron Letters, 2007, 48, 8220–8222.
18. X. Fu, Z. Jiang and C.-H. Tan, Bicyclic guanidine-catalyzed enantioselective Phospha-Michael
reaction: Synthesis of chiral β-aminophosphine oxides and β-aminophosphines, Chemical Communications, 2007, 5058–5060. 19. W. Ye, Z. Jiang, Y. Zhao, Serena L. M. Goh, D. Leow, Y.-T. Soh and C.-H. Tan. Chiral bicyclic
guanidine as a versatile Brønsted base catalyst for the enantioselective Michael reactions of dithiomalonates and β-keto thioesters, Advanced Synthesis and Catalysis, 2007, 349, 2454–2458.
20. S.M. Ong, L. He, N.T.T. Linh, Y.H. Tee, T. Arooz, G.P. Tang, C.H. Tan and Yu H. Transient
inter-cellular polymeric linker. Biomaterials, 2007, 28, 3656–3667.
21. J. Shen and C.-H Tan, Brønsted-Acid and Brønsted-Base catalyzed Diels–Alder reactions,
Organic and Biomolecular Chemistry, 2007, 6, 3229–3236. (Invited)
(2008)
22. H. Liu, Y. Pan and C.-H. Tan, Sodium nitrite (NaNO2) catalysed iodo-cyclisation of alkenes and
alkynes using molecular oxygen. Tetrahedron Letters, 2008, 49, 4424–4426.
23. D. Leow, S. Lin, S. K. Chittimalla, X. Fu and C.-H. Tan, Enantioselective protonations catalyzed
by chiral bicyclic guanidine, Angewandte Chemie International Edition English, 2008, 47, 5641–5645. (Highlighted by Synfacts 2008, 9, 0933-0933; contributors: Benjamin List, Frank Lay)
24. J. Xu, X. Fu, R. Low, Y.-P. Goh, Z. Jiang and C.-H. Tan, Tandem conjugate Addition-
Elimination reaction promoted by Chiral Pyrrolidinyl Sulphonamide (CPS), Chemical Communications, 2008, 5526–5528. (Highlighted by Douglass F. Taber, Org. Chem. Highlights 2009, August 10.)
25. Z. Jiang, W. Ye, Y. Yang and C.-H. Tan, Rate acceleration of triethylamine-mediated guanidine-
catalyzed enantioselective Michael reaction, Advanced Synthesis and Catalysis, 2008, 350, 2345 – 2351.
26. J. Shen and C.-H. Tan, Anthrone-Derived NHPI analogues as catalysts in reactions using oxygen
as an oxidant, Organic and Biomolecular Chemistry, 2008, 6, 4096–4098.
27. Y. Wang, M. T. T. Ng, T. Zhou, X. Li, C.-H. Tan and T. Li, C3-Spacer-Containing circular
oligonucleotides as inhibitors of Human Topoisomerase I. Bioorganic and Medicinal Chemistry Letters, 2008, 18, 3597–3602.
28. L. Li, M. Whiteman, Y. Y. Guan, K. L. Neo, Y. Cheng, S. W. L, Y. Zhao, R. Baskar, C.-H. Tan
and P. K. Moore, Characterisation of a novel, water soluble hydrogen sulfide releasing molecule (GYY4137): new insights into the biology of hydrogen sulphide, Circulation, 2008, 117, 2351–2360.
29. S. M. Ong, C. Zhang, Y. C. Toh, S. H. Kim, H. L. Foo, C.-H. Tan, D. van Noort, S. Park and H.
Yu, A gel-free 3D microfluidic cell culture system, Biomaterials, 2008, 29, 3237–3244.
30. R.-S. Liu, V. Drozd, N. Bagkar, C.-C. Shen, I. Baginskiy, C.-H. Chen and C.-H. Tan. Direct
white light phosphor based on metallorganic coordination extended networks for UV-light-emitting diodes Journal of the Electrochemical Society, 2008, 155 (6), P71-P73.
31. D. Q. Zhao, Z.L. Yue, S. M. Ong, Y.C. Toh, Z.Y. Jiang, C.-H Tan, J.P. Chen and H. Yu, Novel
hydrazide dendrimer as transient inter-cellular linker, Biomaterials, 2008, 29, 3693–3702.
32. C.-H Tan and J. Shen. 2,3,5,6-Tetrahydro-2,6-bis(phenylmethyl)-1H-imidazo[1,2-a]imidazole,
Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS), 2008, DOI: 10.1002/047084289X.rn00967. Article Online Posting Date: September 15, 2008. (Invited)
(2009)
33. D. Leow and C.-H. Tan, Chiral guanidines catalyzed enantioselective reactions, Chemistry - An
Asian Journal, 2009, 4, 488–507. (Invited, Most accessed articles 6/2008–5/2009)
34. Z. Jiang, Y. Yang, Y. Pan, Y. Zhao, H. Liu and C.-H. Tan, Enantioselective conjugate addition of
1,4-unsaturated dicarbonyl compounds: Umpolung approach towards amides and ketones with α-stereogenic center, Chemistry - An European Journal, 2009, 15, 4925–4930.
35. R. Lee, X. Lim, T. Chen, G. K. Tan, C.-H. Tan and K.-W. Huang. Selective formation of bicyclic
guanidinium chloride complexes: Implication of the bifunctionality of guanidines. Tetrahedron Letters, 2009, 50, 1560–1562.
36. Julian Y.-T. Soh, C.-H. Tan, Amino-Indanol catalyzed enantioselective reactions of 3-Hydroxy-
2-Pyridones, Journal of the American Chemical Society, 2009, 131, 6904–6905. (Highlighted by Synfacts 2009, 7, 0792-0792; contributors: Benjamin List, Saihu Liao)
37. H. Liu, D. Leow, C.-H. Tan, Enantioselective synthesis of chiral allenes by guanidine-catalyzed
isomerization of alkynes, Journal of the American Chemical Society, 2009, 131, 7212–7213. (Highlighted by Synfacts 2009, 7, 0794-0794; contributors: Benjamin List, Steffen Müller)
38. Z. Jiang, Y. Pan, Y. Zhao, T. Ma, R. Lee, Y. Yang, K.-W. Huang, M. W. Wong and C.-H. Tan,
Synthesis of chiral quaternary C-F bond through highly enantioselective and diastereoselective guanidine-catalyzed addition of fluorocarbon nucleophiles, Angewandte Chemie International Edition, 2009, 48, 3627 –3631. (Designated by Editors as Hot paper)
39. Q. Sun, R. Collins, S. Huang, L. Holmberg-Schiavone, G. S. Anand, C.-H Tan, S. van-den-
Berg, L.-W. Deng, P. K. Moore, T. Karlberg and J. Sivaraman. Structures of human cystathionine -gamma-Lyase reveal new insights into the mechanism of H2S production, Journal of Biological Chemistry, 2009, 284, 3076–3085.
40. L. Li, M. Salto-Tellez, C.-H. Tan, M. Whiteman, P. K. Moore. GYY4137, A novel hydrogen
sulfide releasing molecule, protects against endotoxic shock in the rat, Free Radical Biology & Medicine, 2009, 47, 103–113.
41. T. Zhou, X. Li, M. T. T. Ng, Y. Wang, N. M. Quek, J. Luo, W. Yuan, C.-H. Tan, H. Zeng, T. Li.
Synthesis and characterization of circular structures of i-Motif tagged with Fluoresceins Bioconjugate Chemistry, 2009, 20, 644–647.
42. X. Fu, W.-T. Loh, Y. Zhang, T. Chen, H. Liu, J. Wang, and C.-H. Tan, Chiral guanidinium salt
catalyzed enantioselective Phospha-Mannich reactions, Angewandte Chemie International Edition, 2009, 2009, 40, 7387–7390. (Highlighted by Synfacts 2009, 11, 1281-1281; contributors: Benjamin List, Lars Ratjen)
43. S. Lin, D. Leow, K.-W. Huang, C.-H. Tan. Enantioselective protonation of itaconimides with
thiols and insights into the rotational kinetics of the axially chiral C–N bond, Chemistry An Asian Journal, 2009, 4, 1741–1744.
(2010)
44. R. Lee, Y. Yang, G. K. Tan, C.-H. Tan, K.-W. Huang. A novel heteroleptic paddlewheel
diruthenium bicyclic guanidinate complex: Synthesis, structure, and scope, Dalton Transactions, 2010, 39, 723 – 725.
45. S. Huang, J. H. Chua, W. S. Yew, J. Sivaraman, P. K. Moore, C.-H. Tan, L.-W. Deng. Site-
directed mutagenesis on human Cystathionine-gamma-lyase reveals insights into the modulation of H2S production, Journal of Molecular Biology, 2010, 396, 708 – 718.
46. Y. Pan, Y. Zhao, T. Ma, Y. Yang, H. Liu, Z. Jiang, C.-H. Tan, Enantioselective synthesis of α-
fluorinated β-amino acid derivatives via asymmetric Mannich reaction and selective decarboxylation/deacylation reactions, Chemistry - An European Journal, 2010, 16, 779 – 782.
47. M. Whiteman, L. Li, P. C. Rose, C.-H. Tan, D. Parkinson, Philip K. Moore, The effect of
hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages, Antioxidant and Redox Signaling, 2010, 12, 1147 – 1154.
48. H. Liu, W. Feng, Y. Zhao, D. Leow, Y. Pan, C.-H. Tan, Organic dye photocatalyzed α-
oxyamination through irradiation with visible light, Green Chemistry, 2010, 12, 953 – 956. 49. D. Leow, C.-H. Tan, Catalytic reactions of chiral guanidines and guanidinium Salts, Synlett,
50. X. Mo, Q. Li, L. Wai Y. L., B. Zheng C. H. Kang, B. Nugraha, Z. Yue, R. R. Jia, H. X. Fu, D. Choudhury, T. Arooz, J. Yan, C. T. Lim, S. Shen, C.-H. Tan, Hanry Yu, Rapid construction of
mechanically-confined multi-cellular structures using dendrimeric intercellular linker,
Biomaterials, 2010, 31, 7455 – 7467.

51. J. Wang, H. Liu, Y. Fan, Y. Yang, Z. Jiang, C.-H. Tan Bicyclic guanidine-catalyzed direct
asymmetric allylic addition of N-aryl alkylidene-succinimides, Chemistry - An European Journal, 2010, 16, 12534 – 12537.
52. H. Liu, W. Feng, D. Leow, W.-T. Loh, C.-H. Tan, Brønsted-base catalyzed tandem
isomerization-Michael reactions of alkynes: The synthesis of oxacycles and azacycles, 2010, Advanced Synthesis and Catalysis, 352, 3373 – 3379.
(2011)
53. Y. Zhao, Y. Pan, H. Liu, Y. Yang, Z. Jiang, K.-W. Huang, C.-H. Tan, α-Fluorinated aromatic
ketone as nucleophile in asymmetric organocatalytic C-C and C-N bonds formation reactions: A facile route to the construction of fluorinated quaternary stereogenic carbon centers, Chemistry - An European Journal, 2011, 17, 3571–3574.
54. T. Ma, X. Fu, C. W. Kee, L. Zong, Y. Pan, K.-W. Huang, C.-H. Tan, Pentanidium catalyzed
enantioselective phase transfer conjugate addition reactions, Journal of the American Chemical Society, 2011, 133, 2828–2831. (Highlighted by Synfacts 2011, 5, 0556-0556; contributors: Benjamin List, Saihu Liao) 55. Y. Zhang, C. W. Kee, Richmond Lee, X. Fu, Julian Y.-T. Soh, Esther M. F. Loh, K.-W. Huang and Choon-Hong Tan, C.-H. Tan, Guanidine-catalyzed enantioselective desymmetrization of
meso-aziridines, 2010, Chemical Communications, 47, 3897–3899.

56. B. Cho, C.-H. Tan, M.-W. Wah, Sequential catalytic role of bifunctional bicyclic guanidine in
asymmetric Phospha-Michael reaction, Organic and Biomolecular Chemistry, 2011, 9, 4550–4557.
57. Y. Pan, C.-H. Tan, Catalytic decarboxylative reactions, a biomimetic approach inspired from
polyketides biosynthesis, Synthesis, 2011, 13, 2044–2053. (Invited)
58. Z. W. Lee, J. Zhou, C.-S. Chen, Y. Zhao, C.-H. Tan, Ling Li, P. K. Moore, L.-W. Deng, The
slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo, PLoS ONE, 2011, 6, e21077.
59. X. Fu, C.-H. Tan, Mechanistic considerations of guanidines-catalyzed reactions, 2010, Chemical
Communications, 2011, 47, 8210–8222. (Invited)
60. W. Yang, X. Wei, Y. Pan, Richmond Lee, B. Zhu, H. Liu, L. Yan, K.-W. Huang, C.-H. Tan, Z.
Jiang, Highly enantio- and diastereoselective synthesis of β-Methyl-γ-Monofluoro-Methyl substituted alcohols, Chemistry - An European Journal, 2011, 17, 8066–8070 (Designated as VIP – Very Important Paper).
61. Y. Pan, C. W. Kee, Z. Jiang, T. Ma, Y. Zhao, Y. Yang, H. Xue, C.-H. Tan, Expanding the utility
of Brønsted base catalysis: Biomimetic enantioselective decarboxylative reactions, Chemistry - An European Journal, 2011, 17, 8363–8370. 62. B. Nugraha, X. Hong, X. Mo, L. Tan, W. Zhang, P.-M. Chan, C. H. Kang, Y. Wang, L. T. Beng, W. Sung, D. Choudhury, J. M. Rubens, M. McMillian, J. Silva, S. Dallas, C.-H. Tan, Z. Yue,
Hanry Yu, Galactosylated cellulosic sponge for multi-well drug safety testing, Biomaterials,
2011, 32, 6982–6994.
63. B. Zhu, L. Yan, Y. Pan, R. Lee, H. Liu, Z. Han, K.-W. Huang, C.-H. Tan, Z. Jiang,
Enantioselective Lewis Base-catalyzed highly enantioselective allylic hydroxylation of Morita-Baylis-Hillman carbonates with water, Journal of Organic Chemistry, 2011, 76, 6894–6900.
64. Y. L. Quek, C.-H. Tan, J. Bian, D. Huang, Air oxidation of HS- catalyzed by an mixed-valence
diruthenium complex, an near-IR probe for HS- detection, Inorganic Chemistry, 2011, 50, 7379–7381.
65. Y. Pan, C. W. Kee, L. Chen and C.-H. Tan, Environmentally benign, metal-free cross
dehydrogenative coupling reactions catalysed by Rose Bengal with visible light irradiation, Green Chemistry, 2011, 13, 2682–2685.
66. F. Zhao, W. Zhang, Y. Yang, Y. Pan, W. Chen, H. Liu, L. Yan, C.-H. Tan, Z. Jiang, Synthesis of
sulfur-substituted α-stereogenic amides and ketones: Highly enantioselective Sulfa-Michael Addition (SMA) of 1,4-dicarbonyl but-2-enes, Advanced Synthesis and Catalysis, 2011, 353, 2624 – 2630.
67. Y. Pan, S. Wang, C. W. Kee, E. Dubuisson, K. P. Loh, and C.-H. Tan, Rose Bengal and
Graphene Oxide: Oxidative C-H functionalization of tertiary amines using visible Light, Green Chemistry, 2011, 13, 3341–3344.
(2012)
68. Y. Zhao, Y. Pan, S.-B. D. Sim, C.-H. Tan, Enantioselective Fluorination Using Fluorocarbon
Nucleophiles, Organic and Biomolecular Chemistry, 2012, 10, 479–485. (Invited)
69. J. Wang, J. Chen, C. W. Kee, C.-H. Tan, Bicyclic Guanidine-Catalyzed Enantiodivergent γ-
Selective Asymmetric Allylic Amination, Angewandte Chemie International Edition, 2012, 51, 2382 –2386.
70. W. Yang, D. Tan, R. Lee, L. Li, Y. Pan, K.-W. Huang, C.-H. Tan, Z. Jiang, Catalytic
Diastereoselective Tandem Conjugate Addition-Elimination Reaction of Morita-Baylis-Hillman C-Adducts via C–C Bond Cleavage, Chemistry - An Asian Journal, 2012, 7, 771–777.
71. Y. Zhao, X. Lim, Y. Pan, L. Zong, C.-H. Tan, K.-W. Huang, Asymmetric H/D exchange
reactions of fluorinated aromatic ketones, Chemical Communications, 2012, 48, 5479 – 5481.
72. L. Li, W. Chen, W. Yang, Y. Pan, H. Liu, C.-H. Tan, Z. Jiang, Bicyclic Guanidine-Catalyzed
Asymmetric Michael Additions of 3-Benzyl-substituted Oxindoles to N-Maleimides, Chemical Communications, 2012, accepted.
73. K. S. Goh, C.-H. Tan, Metal-Free Pinnick-type Oxidative Amidation of Aldehydes, RSC
74. P. K. Moore, C.-H. Tan, L. Li, Y. Guan. Identification of morpholin-4-ium 4
methoxyphenyl(morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent, US Patent and Trademark Office, US2010/0273743 (Oct 28, 2010). 75. C.-H. Tan, K-W Huang, T. Ma, X. Fu. A Novel Phase Transfer Catalyst, US Provisional
76. P. K. Moore, L. W. Deng, C.-H. Tan, L. Li. The slow-releasing hydrogen sulfide donor,
GYY4137, exhibits novel anti-cancer effects in vitro and in vivo, US Provisional Application No.: 61/483,402. CONFERENCE PAPERS AND PRESENTATIONS (SELECTED)
1. C.H.Tan, A.B.Holmes and T.Stork. Synthesis of the indolizidine core of allopumiliotoxins.
Abstracts of Papers of the American Chemical Society, 1998, Vol.216, No.Pt2, pp.546-ORGN. (Poster)
2. C.H. Tan, The Development of a New Class of Organocatalyst, Singapore-China
Collaborative and Cooperative Chemistry Symposium, Soochow University, 7-8 Apr 2004,
China 2004. (Invited Speaker)
3. C. H. Tan, Chiral guanidine catalyzed Michael reactions. Singapore International Chemical
Conference-4, 8-10 Dec 2005 Singapore. (Oral) 4. C. H. Tan, Chiral guanidine catalyzed Michael reactions, 4th Singapore-India Collaborative
and Cooperative Symposium (SInCCCS4), 20-21 Feb 2006, Singapore. (Invited Speaker) 5. C.H. Tan, W. Ye. Enantioselective Michael reactions catalyzed by a chiral bicyclic guanidine,
The 232nd ACS National Meeting, San Francisco, CA, USA, September 10-14, 2006, ORGN
22. (Oral)
6. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions.9th International Symposium
for Chinese Organic Chemists and 6th International Symposium for Chinese Inorganic Chemists. 17-21 December 2006, Singapore. (Oral) 7. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. 4th Singapore-China
Collaborative and Cooperative Chemistry Symposium, Zhejiang University, Hangzhou, 26th
and 27th October 2007. (Invited Speaker)
8. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. C&CF 2007 International
Symposium on Catalysis and Fine Chemicals, Nanyang Technological University, 19th Dec
2007 Singapore. (Oral)
9. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. 1st Japan-Singapore
Bilateral Symposium on Catalysis. 6-9 Jan 2008, Singapore. (Invited Speaker) 10. C. H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions. UK-SINGAPORE
SYMPOSIUM on Contemporary Organic Synthesis, Methods and Techniques, Biopolis, Singapore, 27 Feb 2008. (Invited Speaker) 11. C. H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions. 43rd EUCHEM
Conference on Stereochemistry 2008. Fürigen/Bürgenstock, Switzerland 12-18 Apr. (Poster)
12. C. H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions. 17th Gordon
Research Conference Stereochemistry 2008. Salve Regina University, Newport, RI, USA 27
July – 1 Aug. (Poster)
13. C. H. Tan, Part 1: Chiral guanidine catalyzed enantioselective reactions; Part 2: Chiral
pyrrolidine-promoted tandem conjugate addition-elimination, Andrew B. Holmes 65th
Birthday Symposium, Department of Chemistry, University of Cambridge, UK, 5 Aug 2008
(Invited Speaker).
14. C. H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions. 3rd International
Conference on Cutting-Edge Organic Chemistry in Asia under Asian Core Program.
Hangzhou China October 19-23, 2008. (Poster)
15. C. H. Tan, Enantioselective Brønsted Base Catalyzed Diels-Alder Reactions. 2nd Japan-
Singapore Bilateral Symposium on Catalysis. 6-7 Jan 2009, Kyoto University, Japan. (Invited
Speaker)
16. C. H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions. 44rd EUCHEM
Conference on Stereochemistry 2009. Brunnen/Bürgenstock, Switzerland 17-22 May. (Poster)
17. C. H. Tan, Bronsted base catalyzed protonation and alkyne isomerization. SPMS Conference,
Nanyang Technological University, 21th July 2009 Singapore. (Invited Speaker)
18. C. H. Tan, Chiral Guanidine Catalyzed Enantioselective Reactions, The 4th International
Symposium for Young Elements Chemists 2009 Workshop on Organometallic Chemistry, Kyushu University, 28-29 Oct Japan. (Invited Speaker) 19. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. NUS – University of
Hyderabad Bilateral Chemistry Symposium. 14-15 Dec 2009, Singapore. (Invited Speaker) 20. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. Singapore International
Chemical Conference-4. 15-18 Dec 2009, Singapore. (Invited Speaker) 21. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. NUS – Seoul National
University Joint Symposium. 5 Mar 2010, Singapore. (Invited Speaker) 22. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, 1st Annual World
Congress of Catalytic Asymmetric Synthesis Beijing International Convention Centre. 20 May 2010, Beijing, China. (Invited Speaker) 23. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. Inaugural Conference on
Molecular & Functional Catalysis ICMFC 2010. 14 July 2010, Singapore. (Invited Speaker) 24. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. The 5th International
Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5) / The 1st New phase International Conference on Cutting-Edge Organic Chemistry in Asia (NICCEOCA-1), 8 Nov 2010, Hsinchu, Taiwan. (Invited Speaker) 25. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions. The 1st International
Collaborative and Cooperative Chemistry Symposium, 15 Nov 2010, Singapore. (Invited Speaker) 26. C. H. Tan, Random Thoughts on Chiral Brønsted Base Catalyzed Enantioselective Reactions.
The International Chemical Congress of Pacific Basin Societies, 17 Dec 2010, Honolulu, Hawaii, USA. (Invited Speaker) 27. C. H. Tan, Organic Dye-Catalyzed Photoredox Chemistry Using Visible Light. GSK-
Singapore Partnership for Green and Sustainable Manufacturing Symposium, 7 July 2011, Singapore. (Invited Speaker) 28. C. H. Tan, Chiral Bronsted Base Catalyzed Enantioselective Reactions. 14th Asian Chemical
Congress, Bangkok, 6 Sep 2011. (Invited Speaker) 29. C. H. Tan, Organic Dye-Catalyzed Photoredox Chemistry Using Visible Light. 2nd
International Conference on Green and Sustainable Chemistry, 16 Nov 2011, Singapore. (Keynote Speaker) 30. C. H. Tan, Guanidine-Catalyzed Asymmetric Tandem-Isomerisation Intramolecular-Diels-
Alder Reaction: Total Synthesis of (+)-alpha-Yohimbine, 2nd NTU-Ecole Polytechnique Workshop, NTU, Singapore, 20 Feb 2012. (Invited Speaker)
INVITED LECTURES
1. C. H. Tan, Organocatalytic Reactions - Chiral Guanidine and Chiral Imidazoline, S*Bio Pte
Ltd , 17 Jan 2007 Singapore.

2. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Wyeth Research,
3. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Boston University, Boston, MA, 11 Apr 2007.
4. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Brandeis University, Waltham, MA, 12 Apr 2007.
5. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
National Taiwan University, Taipei, Taiwan, 11 May 2007.
6. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
National Tsing Hua University, Hsingchu, Taiwan, 18 May 2007.
7. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
National Cheng Kung University, Tainan, Taiwan, 13 June 2007.
8. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
National Sun Yat-Sen University, Kaohsiung, Taiwan, 14 June 2007.
9. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
The University of Hong Kong, Hong Kong, 11 Mar 2008.
10. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Hong Kong University of Science and Technology, Hong Kong, 12 Mar 2008.
11. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Chinese University of Hong Kong, Hong Kong, 13 Mar 2008.
12. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
ETH Zürich (Eidgenössische Technische Hochschule Zürich) Swiss Federal Institute of
Technology, 11 Apr 2008.
13. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
University of Minnesota, Minneapolis, MN, 23 July 2008.
14. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, School of Pharmacy,
University of Wisconsin at Madison, Madison, WI, 25 July 2008.
15. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Tamkang University, Tamsui, Taiwan, 4 Aug 2008.
16. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
University of Oxford, UK, 3 Aug 2008.
17. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
National Taiwan University, Taipei, Taiwan, 19 Jan 2009.
18. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Institute of Chemistry,
Academia Sinica, Taipei, Taiwan, 20 Jan 2009.
19. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Applied
Chemistry, National Chiao Tung University, Hsingchu, Taiwan, 19 Jan 2009.
20. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Industrial
Chemistry, Faculty of Engineering, Tokyo University of Science, Tokyo, Japan , 10 Mar
2009.
21. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of
Biotechnology and Life Science, Faculty of Technology, Tokyo University of Agriculture
and Technology, Tokyo, Japan , 11 Mar 2009.
22. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Graduate School of
Pharmaceutical Sciences, Department of Chemistry, University of Tokyo, Tokyo, Japan , 12
Mar 2009.
23. C. H. Tan, Chiral guanidine catalyzed enantioselective reactions, Department of Chemistry,
Graduate School of Science, Tohoku University, Sendai, Japan , 13 Mar 2009.
24. C. H. Tan, Bronsted base catalyzed enantioselective reactions, Department of Chemistry,
Chinese University of Hong Kong, Hong Kong, 06 Oct 2009.
25. C. H. Tan, Bronsted base catalyzed enantioselective reactions, Department of Chemistry,
Hong Kong Baptist University, Hong Kong, 07 Oct 2009.
26. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Organic Chemistry, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University,
Japan, 30 Oct 2009.
27. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Organic Chemistry, Graduate School of Pharmaceutical Sciences , Kyoto University, Japan,
31 Oct 2009.
28. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Biotechnology, Graduate School of Engineering, Nagoya University, Japan, 2 Nov 2009.
29. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Chemistry, Gakushuin University, Japan, 4 Nov 2009.
30. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of
Technology, Japan, 5 Nov 2009.
31. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Division of
Chemistry and Biological Chemistry, Nanyang Technological University, 10 Feb 2010.
32. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Chemistry, Faculty of Science, Chulalongkorn University, Thailand, 19 Feb 2010.
33. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, GlaxoSmithKline
R&D China, Singapore Research Centre, Biopolis, Singapore, 2 Mar 2010.
34. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, College of Chemistry
and Molecular Engineering, Peking University, China, 21 May 2010.
35. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, KAUST Catalysis
Centre, King Abdullah University of Science and Technology, Saudi Arabia, 14 June 2010.
36. C. H. Tan, Organic Dye-Catalyzed Photoredox Chemistry Using Visible Light, KAUST
Catalysis Centre, King Abdullah University of Science and Technology, Saudi Arabia, 6
June 2011.
37. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Chulabhorn
Research Institute, Bangkok, 5 Oct 2011.
38. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Shanghai Institute
of Organic Chemistry, Shanghai, 31 Oct 2011.
39. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Shanghai Institute
of Materia Medica, Shanghai, 1 Nov 2011.
40. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, GlaxoSmithKline
R&D China, Shanghai, 1 Nov 2011.
41. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, School of Chemistry
and Chemical Engineering, Nanjing University, Nanjing, 3 Nov 2011.
42. C. H. Tan, Chiral Brønsted Base Catalyzed Enantioselective Reactions, Department of
Chemistry, University of Science and Technology of China, Hefei, 4 Nov 2011.
43. C. H. Tan, Organic Dye-Catalyzed Photoredox Chemistry Using Visible Light, Department
of Biology and Chemistry, City University of Hong Kong, 26 Nov 2011.

AFFILIATION
• American Chemical Society • Singapore National Institute of Chemistry • Cambridge Commonwealth Society
AWARDS AND HONORS
• NUS Faculty of Science, Dean’s Chair (2011) • GSK-SNIC Organic Chemistry Award (2011) • The 5th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5) Lectureship Award from Korea (2010) • The 5th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5) Lectureship Award from China (2010) • Young Chemist Award (2009) • Young Scientist Award (2009) • CRISP award (2009) • JSPS New Scientific Exchange Program (2009) • Asia Core Program Lectureship Award from Hong Kong (2008) • Asia Core Program Lectureship Award from Japan (2008) • UK-Singapore Partners In Science Collaboration Development Awards (2008) AWARDS OF STUDENTS UNDER SUPERVISION
• Jackson Leow Dasheng – Kiang Ai Kim Scholarship
• Lin Shishi – Lijen Industrial Medal for best honours project, CRISP award for best UROPS
student in Faculty, Schering-Plough Gold Medal for best UROPS in Chemistry • Ng Yu Rui – Schering-Plough Gold Medal for best UROPS in Chemistry • Loh Weitian – Singapore National Institute of Chemistry for Best MSc thesis 2010 • Fu Xiao – Runner up, 2010 Reaxys PhD Prize • Liu Hongjun – Best Research Publication Award 2010, Best Graduate Researcher Award 2010, World Future Foundation PhD Prize in Environmental and Sustainability Research 2011 • Kee Choon Wee – President Graduate Fellowship • Ma Ting – Finalist, 2011 Reaxys PhD Prize

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