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AARP MedicareRx Preferred (PDP) plan STEP THERAPY ALGORITHMS Treatment Group Description Step 1 : Metformin Step 2 : Actoplus Met Step 1 : Metformin Step 2 : Actos Step 1 : One of the following: Step 2 : Amitiza Step 1 : One of the following Tier 1 or Tier 2 antidepressants: a. SSRI b. SNRI c. Bupropion d. Mirtazepine Step 2 : Emsam Step 1 : Fome