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KNOW TB: GET LITERATE! Treatment outcomes of new TB cases 2000–2009 Standard regimens for DS-TB, MDR-TB and XDR-TB Patients who have never been treated for TB in the past or have New cases of TB
taken treatment for less than 4 weeks in the past Intensive Phase: 1 pill (FDC) daily
containing: isoniazid, rifampicin,
Continuation Phase:
2000 to 71% in 2009. The treatment success rate of Intensive Phase: A daily injection
Retreatment cases of TB
Patients who have been treated for 4 weeks or more in the past containing: isoniazid, rifampicin, pyrazinamide, ethambutol Source: National Strategic Plan on HIV, STIs and TB 2012-2016, Available at Intensive Phase: 1 pill (FDC) daily
containing: isoniazid, rifampicin,
Continuation Phase: 1 pill (FDC)
daily containing: isoniazid, rifampicin,
The five countries in the world with the
largest number of new TB cases in 2011
MDR-TB patients have a strain of TB that is resistant to one or more Multi-Drug Resistant TB anti-TB drugs i.e. rifampicin and/or isoniazid
Incidence rates per 100,000 population
Intensive Phase: An injection of
oral intake at least six times a week of: Continuation Phase: Oral intake at
least six times a week of: moxifloxacin, XDR-TB patients have a strain of TB that is not only resistant to first-line Extensively Drug Resistant TB
drugs but also resistant to two key classes of second-line anti-TB drugs Intensive Phase: A daily injection
3. South Africa
Continuation Phase: Daily oral
Note: With MDR and XDR-TB, standard regimens can be switched to individualised regimens that are individually designed. 4. Indonesia
Changes are based on a patient’s previous history of treatment and DST (Drug Susceptibility Test) results.
References: National Tuberculosis Management Guidelines 2009; Management of Drug-resistant Tuberculosis. Policy Guidelines, August 2011 5. Pakistan
Source: WHO Global Tuberculosis Report 2012 South Africa has the third highest estimated total burden of TB in the world after China and India. While total TB burden numbers give us a picture of where most cases of TB are located in the world, the incidence rate per 100,000 population gives us an idea of the concentration or density of TB in our population. TB is a highly infectious disease and every active TB case can infect up to 20 people in its surroundings per year. The incidence rate therefore helps to tell us how serious the threat of TB in our population actually is. Data measuring the TB incidence rate per 100,000 population show that South Africa has the highest burden of disease globally, and at a level that is far above China’s and India’s. According to this measure, China drops to 21st place and India to 16th place globally, while Zimbabwe ONE 8(1): e54587. doi:10.1371/journal.
pone.0054587 and Mozambique rise to the 2nd and 3rd places respectively. A large amount of cross-border labour migration occurs between Zimbabwe, Mozambique and South Africa and this makes the concentration of TB in these neighbouring countries worrying.


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Impact of losp treated timber on polystyrene claddings

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