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Cluster Headache - Rare and
Cluster headache is an extraordinarily painful, rare (affects about 1 per 1000, estimated
14,000 Australians) chronic disease affecting five times as many men as
women. Cluster headaches usually develop between the ages of 20 and 40. It occurs
rarely in children and is extremely rare after 70-75. The term „cluster‟ is used as the
attacks usually occur in groups or clusters, typically for several weeks once or twice a
year at the same time of year. The cause of cluster headache is thought to be a disorder
of an “internal clock” in the hypothalamus.
The two main forms of cluster headache are episodic (alternating periods of attacks and remission, 1-8 per day for 7 days to 1 year, between cluster periods pain-free periods of at least 14 days); and chronic lacking remissions, diagnosed after 1 year without remission or if remissions less than 14 days). Children with cluster headache are reported to experience quite short headache periods, from 5-6 days to 3-4 weeks.
Excruciating, boring, burning pain (much more severe than migraine) localized
pain very pronounced behind one eye, commonly radiating to forehead, temple,
cheek and upper gum on same side of face
drooping of eyelid, watering eye that may become bloodshot, running or blocked
attacks of 15 – 180 minutes 1-3 attacks per day
attacks can occur on consecutive days for 6-8 weeks
remission periods of months to years
onset of pain about an hour after going to bed.
There appears to be a link with smoking as most of those affected are, or have been, heavy smokers or their parents smoked. Discontinuing smoking does not appear to provide any relief. Excessive alcohol consumption may also be a risk factor. Further research on risk factors is needed. Studies have shown family history to be a factor and
During cluster headache periods any substance that dilates blood vessels (such as alcohol, glyceryl trinitrate and histamine) will trigger an attack.
Helpful tips for cluster headache sufferers includes taking medication as prescribed, avoiding alcohol during cluster periods, maintaining regular sleep patterns, avoiding high
stress or strenuous physical activity, avoiding high altitude and quitting smoking.
No tests are normally required to diagnose cluster headache as the symptoms are so specific, however it can be misdiagnosed as migraine. A CT scan of the brain at onset will rule out those uncommon cases caused by a brain lesion.
Treatment and Prevention
A specialist medical practitioner should be consulted. Apart from avoiding alcohol during clusters, the main treatment involves taking medication. Acute (treat as attacks start) and prophylactic (preventative, taken every day) medications are used, many sufferers requiring both. Acute medications include oxygen inhalation, sumatriptan subcutaneous injection, ergotamine and intranasal lignocaine. Prophylactic medications include calcium channel blocking agent verapamil with lithium carbonate if necessary, ergotamine, methysergide and corticosteroids such as prednisone. All these medications
should only be taken under the supervision of a medical practitioner.
Migraine and Other Headaches 2000 Professor James Lance Cluster Headache & Related Conditions 2000 Jes Olesen & Peter J. Goadsby Wolff’s Headache and Other Head Pain 7th ed Silberstein, Lipton & Dalessio Understanding Migraine & Other Headaches 2002 Dr Anne MacGregor www.hospital-doctor.cc Headache British Brain and Spine Foundation Headaches Paul Spira Health Essentials Headache Disorders and Public Health, WHO 2000
Prepared by Louise Alexander, PhC, Grad Dip Comm Mngt, Former National Director of the Brain Foundation. Reviewed by Professor James Lance, AO, CBE, MD, Hon DSc, FRCP, FRACP, FAA, Consulting Neurologist, and author, “Migraine and Other Headaches”. www.headacheaustralia.org.au
ABORDAJE FARMACOLÓGICO DEL PACIENTE AGITADO Comisión de Farmacia y Terapéutica X.A.P de Santiago 1. AGITACIÓN ORGÁNICA Deben extremarse las precauciones por los riesgos que supone administrar a un paciente médicamente grave un depresor del SNC. Mientras se resuelve la causa de la agitación, se puede recurrir a la sedación - De primera elección: Haloperidol , 2.5-5 mg IM, re
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