Publikationen-prof.dr.rer.nat.c.heim

Univ.-Prof. Dr. rer. nat. Dipl.-Psych. Christine Marcelle Heim
CharitéCentrum für Human- und Gesundheitswissenschaften
PUBLIKATIONEN
(*Publikationen mit supervisierten Doktoranden/Postdoktoranden)

ORIGINAL- UND REVIEWARTIKEL
Heim, C., Ehlert, U., Rexhausen, J., Hanker, J. P. & Hellhammer, D. H. (1997).
Psychoendocrinological observations in women with chronic pelvic pain. Annals of the New
York Academy of Sciences, 821, 456-458. Impact-Faktor: 0.964; Zitierungen: 16
Heim, C., Owens, M. J., Plotsky, P. M. & Nemeroff, C. B. (1997). The potential role of early
adverse life events in the pathophysiology of major depression and posttraumatic stress
disorder: focus on corticotropin-releasing factor. Annals of the New York Academy of
Sciences, 821, 194-208. Impact-Faktor: 0.964; Zitierungen: 119
Heim, C., Owens, M. J., Plotsky, P. M., & Nemeroff, C. B. (1997). Persistent changes in CNS
CRF systems due to early adverse life events and their relationship to the pathophysiology of
major depression and posttraumatic stress disorder. Psychopharmacology Bulletin, 33, 185-
192. Impact-Faktor: 2.245; Zitierungen: 142
Heim, C., Ehlert, U., Hanker, J. P. & Hellhammer, D. H. (1998). Abuse-related posttraumatic
stress disorder and alterations of the hypothalamic-pituitary-adrenal axis in women with
chronic pelvic pain. Psychosomatic Medicine, 60, 309-318. Impact-Faktor: 3.429; Zitierungen:
206
Ehlert, U., Heim, C. & Hanker, J. P. (1998). Chronische Unterbauchbeschwerden. Welchen
Beitrag kann die Psychoendokrinologie zur Diagnostik des Beschwerdebilds leisten?
Frauenarzt, 39, 782-784.
Ehlert, U. & Heim, C. (1998). Verhaltensmedizin bei Frauen mit chronischen
Unterbauchbeschwerden. Verhaltenstherapie, 8, 106-111. Impact-Faktor: 0.463; Zitierungen:
3
Ehlert U., Heim, C. & Hellhammer D. H. (1999). Chronic pelvic pain as a somatoform disorder.
Psychotherapy and Psychosomatics, 68, 87-94. Impact-Faktor: 2.259; Zitierungen: 64
Heim, C., Ehlert, U., Hanker, J. P. & Hellhammer, D. H. (1999). Psychological and endocrine
correlates of chronic pelvic pain associated with adhesions. Journal of Psychosomatic
Obstetrics and Gynecology, 20, 11-20. Zitierungen: 23
Heim, C. & Nemeroff, C. B. (1999). Prädisponieren frühe Stresserfahrungen für die
Entwicklung einer Depression oder einer Posttraumatischen Belastungsstörung im
Erwachsenenalter? Evidenz aus neurobiologischen Untersuchungen. Psychomed, 1, 21-30.
10. Ehlert, U., Wagner, D., Heinrichs, M. & Heim, C. (1999). Psychobiologische Aspekte der
Posttraumatischen Belastungsstörung. Nervenarzt, 70, 773-779. Impact-Faktor: 0.557; Zitierungen: 30 11. Graham, Y. P., Heim, C., Goodman, S. & Nemeroff, C. B. (1999). The effects of neonatal stress
on brain development. Development and Psychopathology, 11, 545-565. Impact-Faktor: 4.374; Zitierungen: 112 12. Heim, C. & Nemeroff, C. B. (1999). The impact of early adverse experiences on brain systems
involved in anxiety and affective disorders. Biological Psychiatry, 46, 1509-1522. Impact-Faktor: 5.505; Zitierungen: 274 13. Heim, C., Ehlert, U. & Hellhammer, D. H. (2000). The potential role of hypocortisolism in the
pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology, 25, 1-35. Impact-Faktor: 3.369; Zitierungen: 712 14. Heim, C., Newport, D. J., Heit, S., Graham, Y. P., Wilcox, M., Bonsall, R., Miller, A. H. &
Nemeroff, C. B. (2000). Pituitary-adrenal and autonomic responses to stress in adult women with sexual and physical abuse in childhood. Journal of the American Medical Association (JAMA), 284, 592-597. Impact-Faktor: 17.569; Zitierungen: 846 15. Heim, C., Newport, D. J., Bonsall, R., Miller, A. H. & Nemeroff, C. B. (2001). Altered pituitary-
adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse. American Journal of Psychiatry, 158, 575-581. Impact-Faktor: 6.913; Zitierungen: 363 16. Heim, C. & Nemeroff, C. B. (2001). The role of childhood trauma in the neurobiology of mood
and anxiety disorders: pre-clinical and clinical studies. Biological Psychiatry, 49, 1023-1039. Impact-Faktor: 5.505; Zitierungen: 808 17. Heim, C. & Owens, M. J. (2001). Role of early adverse life events in the pathogenesis of
depression. WPA Bulletin on Depression, 5, 3-7. 18. Heim, C., Newport, D. J., Wagner, D., Wilcox, M., Miller, A. H. & Nemeroff , C. B. (2002). The
role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: A multiple regression analysis. Depression Anxiety 15, 117-125. Impact-Faktor: 0.91; Zitierungen: 176 19. Vythilingam, M., Heim, C., Newport, D. J., Miller, A. H., Vermetten, E., Anderson, E., Bronen,
R., Staib, L., Charney, D. S., Nemeroff, C. B. & Bremner, J. D. (2002). Childhood trauma associated with smaller hippocampal volume in women with major depression. American Journal of Psychiatry, 159, 2072-2080. Impact-Faktor: 6.458; Zitierungen: 284 20. Heim, C. & Nemeroff, C. B. (2002). Neurobiology of early-life stress: clinical studies. Seminars
in Clinical Neuropsychiatry, 7, 147-159. Zitierungen: 111 21. Newport, D. J., Heim, C., Owens, M. J., Ritchie, J. C., Ramsey, C. H., Bonsall, R., Miller, A. H. &
Nemeroff, C. B. (2003). Cerebrospinal fluid corticotrophin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis. Neuropsychopharmacology, 28, 569-576. Impact-Faktor: 5.201; Zitierungen: 27 22. Heim, C., Meinlschmidt, G. & Nemeroff, C. B. (2003). Neurobiology of early-life stress and its
relationship to PTSD. Psychiatric Annals, 33, 1-10. Zitierungen: 29 23. *Penza, K., Heim, C. & Nemeroff, C. B. (2003). Neurobiological effects of childhood abuse:
implications for the pathophysiology of depression and anxiety. Archives of Women's Mental Health, 6, 15-22. Zitierungen: 97 24. Nemeroff, C. B., Heim, C., Thase, M. E., Rush, A. J., Schatzberg, A. F., Ninan, P. T., Klein, D. N.,
McCullough, J. P., Weiss, P., Dunner, D. L., Rothbaum, B. O., Kornstein, S., Keitner, G. & Keller, M. B. (2003). Differential responses to psychotherapy versus pharmacotherapy in the treatment of patients with chronic forms of major depression and childhood trauma. Proceedings of the National Academy of Sciences USA, 100, 14293-14296. Impact-Faktor: 10.272; Zitierungen: 239 25. Reeves, W. C., Lloyd, A., Jason, L., Klimas, N., Bleijenberg, G., Evengard, B., White, P., Nisenbaum, R., Vernon, S. & Unger E. B., and the International CFS Group (Abbey, S.,
Campbell, C., Cleare, A., Gantz, N., Glaser, R., Heim, C., Jones, A. B., Jones, J., Karem, K.,
Kenney, K. K., Lange, G., McCormick, K., Miller, A. H., Moldofsky, H., Natelson, B., O'Laughlin,
T., Papanicolaou, D. A., Rajeevan, M., Ranamukhaarchchi, D., Stewart, J., Subedar, N., Tan,
E.) (2003). Identification of ambiguities in the 1994 chronic fatigue syndrome research case
definition and recommendations for resolution. BMC Health Services Research, 3, 25. Impact-
Faktor: 0.676; Zitierungen: 103
26. Newport, D. J., Heim, C., Bonsall, R., Miller, A. H. & Nemeroff, C. B. (2004). Pituitary-adrenal
responses to standard and low dose dexamethasone suppression tests in adult survivors of childhood abuse. Biological Psychiatry, 55, 10-20. Impact-Faktor: 6.159; Zitierungen: 80 27. Heim, C., Bierl, C., Nisenbaum, R., Wagner D. & Reeves, W. C. (2004). Regional prevalence of
fatiguing illnesses in the United States before and after the terrorist attacks of September 11, 2001. Psychosomatic Medicine, 66, 672-678. Impact-Faktor: 3.429; Zitierungen: 17 28. Heim, C., Plotsky, P. M. & Nemeroff, C. B. (2004). The importance of studying the
contributions of early adverse experience to the neurobiology of depression. Neuropsychopharmacology, 29, 641–648. Impact-Faktor: 4.941; Zitierungen: 224 29. Bremner, J. D., Mletzko, T.M., Welter, S. Siddiq, S., Heim, C. & Nemeroff, C. B. (2004).
Treatment of post-traumatic stress disorder with phenytoin (Dilantin®): An open label pilot study. Journal of Clinical Psychiatry, 65, 1559-1564. Impact-Faktor: 4.806; Zitierungen: 37 30. Bremner, J. D., Mletzko, T., Welter, S., Quinn, S., Williams, C., Brummer, M., Siddiq, S., Reed, L., Heim, C. & Nemeroff, C. B. (2005). Effects of phenytoin on memory, cognition and brain
structure in posttraumatic stress disorder. Journal of Psychopharmacology, 19, 159-165.
Impact-Faktor: 3.994; Zitierungen: 39
31. *Meinlschmidt, G. & Heim, C. (2005). Decreased cortisol awakening response after early loss
experience. Psychoneuroendocrinology, 30, 568-576. Impact-Faktor: 4.381; Zitierungen: 47 32. *Wagner, D., Nisenbaum, R., Heim, C., Jones, J. F., Unger, E. R. & Reeves, W. C. (2005).
Psychometric properties of the CDC Symptom Inventory for the assessment of chronic fatigue syndrome. BMC Population Health Metrics, 22, 8-15. Impact-Faktor: 1.358; Zitierungen: 48 33. Jones, J. F., Nicholson, A., Nisenbaum, R., Papanicolaou, D. A., Solomon, L., Heim, C. &
Reeves, W. C. (2005). Orthostatic instability is not present in persons from the general population with chronic fatigue syndrome. American Journal of Medicine, 118, 1415. Impact-Faktor: 4.388; Zitierungen: 23 34. Reeves, W. C., Wagner, D., Nisenbaum, R., Jones, J. F., Gurbaxani, B., Solomon, L., Papanicolaou, D. A., Unger, E. R., Vernon, S. D. & Heim, C. (2005). Chronic fatigue syndrome:
An empirical approach to its definition and study. BMC Medicine, 3, 19. Impact-Faktor: 3.21;
Zitierungen: 132
35. *Nater, U. M., Wagner, D., Papanicolaou, D. A., Solomon, L., Jones, J. F., Unger, E. R., Reeves, W. C. & Heim, C. (2006). Coping styles in cases with chronic fatigue syndrome identified from
the general population in Wichita, Kansas. Journal of Psychosomatic Research, 60, 567-573.
Impact-Faktor: 2.322; Zitierungen: 13
36. Capuron, L., Welberg, L., Heim, C., Wagner, D., Solomon, L., Papanicolaou, D. A., Craddock, R.
C., Miller, A. H. & Reeves, W. C. (2006). Cognitive dysfunction relates to subjective report of mental fatigue in patients with chronic fatigue syndrome. Neuropsychopharmacology, 31, 1777-1784. Impact-Faktor: 5.889; Zitierungen: 24 37. Rajeevan, M. S., Smith, A. K., Dimulescu, I., Unger, E. R., Vernon, S. D., Heim, C., Reeves, W. C.
(2007). Association of glucocorticoid receptor polymorphisms and haplotypes with chronic fatigue syndrome. Genes, Brain, and Behavior, 6, 167-176. Impact-Faktor: 3.533; Zitierungen: 44 38. *Pace, T. W. W., Mletzko, T., Alagbe, O., Nemeroff, C. B., Musselman, D. L., Miller, A. H. & Heim, C. (2006). Increased stress-induced inflammatory responses in male patients with
major depression and increased early life stress. American Journal of Psychiatry, 163, 1630-
1633. Impact-Faktor: 9.127; Zitierungen: 123
39. Heim, C., Wagner, D., Maloney, E., Papanicolaou, D. A., Solomon, L., Jones, J. F., Unger, E. R.
& Reeves, W. C. (2006). Early adverse experience and risk for chronic fatigue syndrome: a population based study. Archives of General Psychiatry, 63, 1258-1266. (Medscape top psychiatry article in November 2006; top 5 most downloaded articles in Archives of General Psychiatry). Impact-Faktor: 13.936; Zitierungen: 94 40. Reeves, W. C., Heim, C., Maloney, E., Youngblood, L. S., Unger, E., Decker, M. J., Jones, J. F. &
Rye, D. B. (2006). Sleep characteristics of persons with CFS and non-fatigued controls: Results from a population-based study. BMC Neurology, 6, 41. Impact-Faktor: 1.903; Zitierungen: 25 41. *Meinlschmidt G. & Heim, C. (2007). Sensitivity to intranasal oxytocin in adult men after
early parental separation. Biological Psychiatry, 61, 1109-1111. Impact-Faktor: 8.456; Zitierungen: 37 42. *Wingenfeld, K., Wagner, D., Schmidt, I., Meinlschmidt, G., Hellhammer, D. H. & Heim, C.
(2007). The low-dose dexamethasone suppression test in fibromylagia. Journal of Psychosomatic Research, 62, 85-91. Impact-Faktor: 1.859; Zitierungen: 23 43. Laures-Gore, J., Heim C. & Hsu, Y. S. (2007). Assessing cortisol reactivity to a linguistic task as
a marker of stress in individuals with left hemisphere stroke and aphasia. Journal of Speech, Language, and Hearing Research, 50, 493-507. 44. Reeves, W. C., Maloney, E., Jones, J. F., Heim, C., Hoaglin, D. C., Boneva, R., Morrissey, M.,
Devlin, R. (2007). Prevalence of chronic fatigue syndrome in metropolitan, urban, and rural Georgia populations. BMC Population Health Metrics, 5, 5. Impact-Faktor: 1.558; Zitierungen: 62 45. Boneva, R.S., Decker, M. J., Maloney, E. M., Lin, J. M., Jones, J. F., Helgason, H. G., Heim, C.,
Rye, D. B. & Reeves, W. C. (2007). Higher heart rate and reduced heart rate variability persist during sleep in chronic fatigue syndrome: A population-based study. Autonomic Neuroscience, 137, 94-101. Impact-Faktor: 1.756; Zitierungen: 26 46. *Majer, M., Jones, J. F., Unger, E. R., Youngblood, L. S., Decker, M. J., Maloney, E., Gurbaxani, B., Heim, C., & Reeves, W. C. (2007). Perception versus polysomnographic assessment of
sleep in CFS and non-fatigued controls: results from a population-based study. BMC
Neurology, 7, 40. Impact-Faktor: 1.903; Zitierungen: 15
47. Ramasubbu, R., Masalovich, S., Peltier, S., Holtzheimer, P. E., Heim, C., Mayberg, H. S. (2007).
Neural representation of maternal face processing: an fMRI study. Canadian Journal of Psychiatry, 52, 726-734. Impact-Faktor: 3.026 48. Heim, C., Newport, D. J., Mletzko, T. M., Bonsall, R., Miller, A. H., & Nemeroff, C. B.
(2008).The link between childhood trauma and depression: Insights from HPA axis studies in humans (2007 Curt Richter Award Paper). Psychoneuroendocrinology, 33, 693-710. Impact-Faktor: 4.422; Zitierungen: 146 49. Heim, C., Mletzko, T., Purselle, D., Musselman, D. L. & Nemeroff, C. B. (2008). The combined
dexamethasone/CRF test in men with major depression: Role of childhood trauma. Biological Psychiatry, 63, 398-405. Impact-Faktor: 8.453; Zitierungen: 83 50. *Wingenfeld, K., Heim, C., Schmidt, I., Meinlschmidt, G., Wagner, D., Hellhammer, D. H.
(2008). HPA axis reactivity and glucocorticoid sensitivity in patients with fibromyalgia syndrome and chronic pelvic pain. Psychosomatic Medicine, 70, 65-72. Impact-Faktor: 3.209; Zitierungen: 32 51. Bradley, R. G., Binder, E. B., Epstein, M., Tang, Y., Nair, H., Liu, W., Gillespie, C. F., Berg, T., Evces, M., Heim, C. M., Nemeroff, C. B., Schwartz, A., Cubells, J. F., Ressler, K. J. (2008).
Influence of child abuse on adult depression: moderation by the corticotropin-releasing
hormone receptor gene. Archives of General Psychiatry, 65, 190-200. Impact-Faktor: 15.976;
Zitierungen: 159
52. *Nater, U. M., Youngblood, L. S., Jones, J. F., Unger, E. R., Reeves, W. C., Heim, C. (2008).
Alterations in diurnal salivary cortisol rhythm in a population-based sample of cases with chronic fatigue syndrome. Psychosomatic Medicine, 70, 298-305. Impact-Faktor: 3.109; Zitierungen: 26 53. Smith, A. K., Dimulescu, I., Narasimhan, S., Heim, C., Vernon, S. D. & Rajeevan, M. S. (2008).
Genetic evaluation of the serotonergic system in chronic fatigue syndrome. Psychoneuroendocrinology, 33, 188-197. Impact-Faktor: 4.422; Zitierungen: 17 54. *Nater, U. M., Maloney, E., Boneva, R. S., Jones, J. F., Reeves, W. C., & Heim, C. (2008).
Attenuated morning salivary cortisol concentrations in a population-based sample of cases with chronic fatigue syndrome and well controls. Journal of Clinical Endocrinology & Metabolism, 93, 703-709. Impact-Faktor: 5.493; Zitierungen: 27 55. Binder, E. B., Bradley, R. G., Liu, W., Epstein, M. P., Deveau, T. C., Tang, Y., Gillespie, C. F., Heim, C. M., Nemeroff, C. B., Schwartz, A. C., Cubells, J. F., & Ressler, K. J. (2008). Risk for
adult posttraumatic stress disorder is predicted by child abuse and FKBP5, a gene regulating
stress-responsiveness. Journal of the American Medical Association (JAMA). 299, 1291-1305.
Impact-Faktor: 25.547; Zitierungen: 214
56. Heim, C., Young, L. J., Newport, D. J., Mletzko, T. C., Miller, A. H., Nemeroff, C. B. (2009).
Persistent CSF oxytocin deficiency after childhood abuse. Molecular Psychiatry, 14, 954-958. [Epub ahead of print Oct 28, 2008]. Impact-Faktor: 10.9; Zitierungen: 47 57. Heim, C., Nater, U.M., Maloney, E. B., Boneva, R., Jones, J. F., & Reeves, W. C. (2009).
Childhood risk factors for chronic fatigue syndrome: Association with neuroendocrine dysfunction. Archives of General Psychiatry, 66, 72-80. (Article included in Faculty of 1000 Medicine). Impact-Faktor: 15.976; Zitierungen: 45 58. Heim, C. & Nemeroff, C. B. (2009). Neurobiology of posttraumatic stress disorder. Consensus
Meeting on PTSD. CNS Spectrums, 14 (Suppl. 1), 13-24. Impact-Faktor: 2.22; Zitierungen: 55 59. Lupien, S. J., McEwen, B. S. Gunnar, M., & Heim, C. (2009). Effects of stress throughout the
lifespan on brain, behavior and cognition. Nature Reviews Neuroscience, 10, 434-445. Impact-Faktor: 26.483; Zitierungen: 274 60. *Nater, U. M., Maloney, E. B., Boneva, R., Jones, J. F., Reeves, W. C., & Heim C. (2009).
Psychiatric comorbidity in a population-based sample with chronic fatigue syndrome. Psychosomatic Medicine, 71, 557-565. Impact-Faktor: 3.109; Zitierungen: 9 61. Heim, C. (2009). New perspective on chronic fatigue syndrome: Lessons from developmental
neuroscience. Future Neurology, 4, 377-381. 62. *Nater, U. M. & Heim, C. The role of stress in chronic fatigue syndrome. International Journal
of Medical & Biological Frontiers: In press. 63. *Nater, U. M., Whistler, T., Lonergan, W., Vernon, S. D., & Heim, C. (2009). Impact of acute
psychosocial stress on peripheral blood gene expression pathways in healthy men. Biological Psychology, 82, 125–132. Impact-Faktor: 4.363 64. Heim, C., Bradley-Davino, B. G., Mletzko, T. C., Deveau, T. C., Musselman, D. L., Nemeroff, C.
B., Ressler, K. J., & Binder, E. B. (2009). Effect of childhood trauma on adult depression and neuroendocrine function: sex-specific moderation by CRH receptor 1 gene. Frontiers in Behavioral Neuroscience, 6, 3:41. Impact-Faktor: 3.396; Zitierungen: 22 65. Wingenfeld, K., Hellhammer, D.H., Schmidt, I., Wagner, D., Meinlschmidt, G., Heim, C. (2009).
HPA axis reactivity in chronic pelvic pain: association with depression. Journal of Psychosomatic Obstetrics and Gynaecology, 30, 282-286. Impact-Faktor: 1.585 66. Heim, C., Shugart, M., Craighead, W.E. & Nemeroff, C.B. (2010). Neurobiological and
psychiatric consequences of child abuse and neglect. Developmental Psychobiology, 52, 671-690. Impact-Faktor: 2.119 67. Dunlop, B.W., Betancourt, Y., Binder, E.B., Heim, C., Holsboer, F., Ising, M., McKenzie, M.,
Mletzko, T., Pfister, H., Nemeroff, C.B., Craighead, W.E., & Mayberg, H.S. (2011). Tolerability of the dexamethasone corticotropin releasing hormone test in major depressive disorder. Journal of Psychiatric Research, 45, 24-28. Impact-Faktor: 3.723 68. Silverman, M. N., Heim, C. M., Nater, U. M., Marques, A. H., & Sternberg, E. M. (2010).
Neuroendocrine and immune contributors to fatigue. Physical Medicine & Rehabilitation, 2, 338-346. 69. *Nater, U.M., Jones, J.F., Lin, J.M., Maloney, E., Reeves, W.C., & Heim, C. (2010). Personality
features and personality disorders in chronic fatigue syndrome: A population-based study. Psychotherapy & Psychosomatics, 79, 312-318. Impact-Faktor: 5.368 70. Pace, T.T.W., & Heim, C. (2011). Psychoneuroimmunology of posttraumatic stress disorder.
Brain, Behavior & Immunity, 25, 6-13. Impact-Faktor: 5.061 71. Wingenfeld, K., Heim, C., Schmidt, I., Spitzer, C., Hellhammer, D.H. (2010). Chronische
Alltagsbelastungen und frühe Traumatisierung: Auswirkungen auf die aktuelle PTSD Symptomatik. Trauma und Gewalt, 3, 214-220. 72. Bradley, B., Westen, D., Jovanovic, T., Binder, E.B., Crain, D., Wingo, A., Heim, C. (2011).
Association between childhood maltreatment and adult emotional dysregulation in a low income, urban, African American sample: Moderation by oxytocin receptor gene. Development and Psychopathology. In press. Impact-Faktor: 4.949 73. Boneva, R. S., Lin, J. S., Maloney, E. M., Jin-Mann, L., Jones, J., Wieser, F., Nater, U., Heim, C.,
& Reeves, W. C. (2011). Gynecologic History in Chronic Fatigue Syndrome (CFS): a population-based case-control study. Journal of Women’s Health 20, 21-28. 74. Wingenfeld, K., Driessen, M., Mensebach, C., Rullkoetter, N., Schaffrath, C., Spitzer, C., Schlosser, N., Beblo, T., & Heim, C. (2011). Die deutsche Version des „Early Trauma
Inventory” (ETI). Erste psychometrische Charakterisierung eines Interviews zur Erfassung
traumatischer Lebensereignisse in der Kindheit und Jugend. Diagnostica, 57, 27-38. Impact-
Faktor: 0.73
75. Pace, T.T.W., Wingenfeld, K., Meinlschmidt, G., Schmidt, I., Hellhammer, D. H., Heim, C.
(2011). Increased peripheral NF-kappa B pathway activity in women with childhood abuse-related posttraumatic stress disorder. Brain, Behavior & Immunity, Jul 27 2011 Epub. Impact-Faktor: 5.061 76. Nater, U. M., Maloney, E., Heim, C., & Reeves, W. C. (2011). Cumulative life stress in chronic
fatigue syndrome. Psychiatry Research, Sept 14 2011 Epub. Impact-Faktor: 2.803 77. Ramasubbu, R., Masalovich, S., Gaxiola, I., Peltier, S., Holtzheimer, P.E., Heim, C., Goodyear,
B., Macqueen, G., Mayberg, H.S., 2011. Differential neural activity and connectivity for processing one's own face: A preliminary report. Psychiatry Research, 194, 130-140. Impact-Faktor: 2.803 VERÖFFENTLICHTE BRIEFE
Heim, C., Newport, D. J., Miller, A. H. & Nemeroff, C. B. (2000). The role of gender or
retrospective self-reports as modulators of findings on increased stress reactivity after
childhood abuse. Journal of the American Medical Association (JAMA), 284, 2322. Impact-
Faktor: 17.569; Zitierungen: 32
Heim, C., Newport, D. J., Miller, A. H. & Nemeroff, C. B. (2001). Effects of ethnicity on findings
on neuroendocrine function after childhood abuse. American Journal of Psychiatry, 159, 158-
159. Impact-Faktor: 6.913

ZUSAMMENFASSUNG DER PUBLIKATIONEN (PEER-REVIEWED)
Impact-Faktor der Erst- und Letztautorenschaften: Zitierungen der Erst- und Letztautorenschaften: BÜCHER
1.
Heim, C. (1996). Psychoendokrinologische Untersuchung von Frauen mit chronischen
Unterbauchbeschwerden. Aachen: Shaker Verlag.

BUCHKAPITEL
Ehlert, U., Heim, C. & Rösner, A. (1995). Behavioral medicine in gynecology:
psychoendocrinological correlates of female infertility. In M. Stauber (Ed.), Proceedings of the
11th International Congress of Psychosomatic Obstetrics and Gynecology (pp. 301-308).
Bologna: Monduzzi.
Hellhammer, D. H., Kirschbaum, C., Heim, C. & Ehlert, U. (1996). Differences of pituitary-
adrenal reactivity in men. In Schriftenreihe der Bundesanstalt für Arbeitsmedizin (Ed.),
Occupational Health and Safety Aspects at Modern Work Places (pp. 62-65). Berlin: Wirtschaftsverlag. Heim, C. & Ehlert, U. (1997). Zur Diagnostik sexuellen Mißbrauchs und der daraus
resultierenden psychischen Auffälligkeiten. In G. Ammann & R. Wipplinger (Hrsg.), Sexueller
Mißbrauch (S. 333-354). Tübingen: dgvt-Verlag.
Ehlert, U., Heim, C. & Hellhammer, D. H. (1998). Somatoforme Störungen: Dysregulation der
Hypophysen-Nebennierenrinden-Achse am Beispiel chronischer Unterbauchbeschwerden. In
G. Rudolf & P. Henningsen (Hrsg.), Somatoforme Störungen. Aktuelle Entwicklungen in der
psychotherapeutischen Medizin (S. 235-247). Stuttgart: Schattauer Verlag.
Hellhammer, D. H., Heim, C. & Buske-Kirschbaum, A. (1998). Biochemische Ansätze in der
Klinischen Psychologie. In M. Perez & U. Baumann (Hrsg.), Lehrbuch der Klinischen
Psychologie. Grundlagen (S. 177-1991). Bern: Hans Huber.
Nemeroff, C. B., Heim, C., Owens, M. J. & Plotsky, P. M. (1999). Neurochemical mechanisms
underlying depression and anxiety disorders: the influence of early trauma. In New
Developments in Understanding Depression and Its Treatment: Proceedings of a Symposium
Held During the 21st CINP Congress (pp. 3-6). Washington Crossing, PA: Scientific Frontiers,
Inc.
Heim, C. & Ehlert, U. (1999). Pharmakologische Provokationstests zur Einschätzung der
neuroendokrinen Funktion. In C. Kirschbaum & D. H. Hellhammer (Hrsg.), Enzyklopädie der
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10. Heim, C. & Nemeroff, C. B. (2002). Neurobiology of Early Life Stress and its Disorders. In A.
Martin, L. Scahill, D. Charney & F. Leckman (Eds.), Textbook of Pediatric Psychopharmacology (pp. 110-124). New York, NY: Oxford University Press. 11. Heim, C. & Meinlschmidt, G. (2002). Biologische Grundlagen. In U. Ehlert (Hrsg.), Lehrbuch
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Hoffmann, P. Joraschky, Sexueller Missbrauch, Misshandlung, Vernachlaessigung (3. Auflage). Stuttgart: Schattauer-Verlag. 13. *Penza, K., Heim C. & Nemeroff, C. B. (2005). Loss and deprivation: from animal models to
clinical presentation. In J. Licinio & M. L. Wong (Eds.). Biology of Depression: Towards a Novel Understanding and Therapeutic Strategies. Psychosocial Aspects and Animal Models Section. Hoboken, NJ: John Wiley & Sons. 14. *Penza, K., Heim C. & Nemeroff, C. B. (2005). Trauma and depression. In C. L. M. Keyes & S.
H. Goodman (Eds.). Handbook for the Study of Women and Depression. Social, Political, and Economic Models of Risk. Cambridge: University Press. 15. Heim, C., Wingenfeld, K. & Ehlert, U. (2005). Zur Erfassung sexuellen Missbrauchs und daraus
resultierender psychischer Auffälligkeiten. In G. Amann, R. Wipplinger R. (Hrsg.), Sexueller Mißbrauch, 2. Aufl. Tübingen: dgvt-Verlag. 16. Matzen, K., Ehlert, U. & Heim, C. (2005). Sexueller Missbrauch und chronische
Unterbauchbeschwerden. In G. Amann, R. Wipplinger (Hrsg.), Sexueller Mißbrauch (2. Auflage). Tübingen: dgvt-Verlag. 17. Heim, C. (2005). Brain/Gut: Neuroendocrinology of Stress (pp.18-21). Basic Principles.
Brain/Gut Interactions. Proceedings of the 6th International Symposium on Functional Gastrointestinal Disorders. International Foundation of Functional Gastrointestinal Disorders, Milwaukee, WS. 18. Heim, C., Bremner, J. D. & Nemeroff, C. B. (2006). Trauma spectrum disorders. In M. S. Runge
& C. Patterson (Eds.) Principles of Molecular Medicine (pp. 1203-1210). Totowa, NJ: Humana Press. 19. *Wagner, D., Schmidt, I. & Heim C. (2006). Psychobiologie der Posttraumatischen
Belastungsstörung (pp. 321-337). In A. Remmel, O. F. Kernberg, W. Wollmöller & B. Strauss (Hrsg.), Körper und Persönlichkeit. Diagnostik und Therapie gestörter Entwicklung. Stuttgart: Schattauer-Verlag. 20. Heim, C. & Nater, U. M. (2007). Hypocortisolism and stress. In G. Fink, G. Chrousos, I. Craig, E.
R. de Kloet, G. Feuerstein, B. S. McEwen, N. Rose, R. Rubin, A. Steptoe (Eds), Encyclopedia of Stress, Second Edition. Oxford: Elsevier. 21. Angold, A.A. & Heim, C. (2007). A developmental perspective, with a focus on childhood
trauma (pp. 81-100). In W.E. Narrow, M. B. First, P. J. Sirovatka & D. A. Regier (Eds.), Age and Gender Considerations in Psychiatric Diagnosis. A Research Agenda for DSM-V: Role of Gender Differences. Arlington, VA: American Psychiatric Association. 22. *Nater, U. M. & Heim, C. (2008). Childhood trauma and functional somatic syndromes. In C.
Worthman, D. Schechter, P.M. Plotsky, C. Cummings (Eds), Formative Experiences: The Interaction of Caregiving, Culture, and Developmental Psychobiology. Section III. Developing Brains, Developing Selves: Interactions of Persons and Experiences across Generations. Cambridge University Press. 23. Heim, C., Nemeroff, C.B. (2008). Neurochemistry. In G. Reyes, J. Elhai, J. Ford (Eds.),
Encyclopedia of Psychological Trauma. New York, NY: Wiley and Sons, Inc. 24. Heim, C. (2009). Childhood trauma and adult stress responsiveness. In Encyclopedia on Early
Childhood Development. The Scientific Committee of the Early Childhood Learning Knowledge Centre (ECLKC) and Centre of Excellence for Early Childhood Development (CEECD). http://www.enfant-encyclopedie.com/pages/PDF/HeimANGxp.pdf 25. Haroon, E. B., Pagnoni, G., Heim, C., Berns, G. S. & Mayberg, H. S. (2009). Brain imaging in
psychopharmacology. In A. F. Schatzberg & C. B. Nemeroff (Eds.), Section Part 1, Principles of Psychopharmacology, R. Malenka (Section Ed.), Textbook of Psychopharmacology, 4th Edition. Arlington, VA: American Psychiatric Publishing, Inc. 26. *Nater, U. M., Heim, C., & Raison, C. L. Chronic fatigue syndrome (2010). In M. J. Aminoff, F.
Boller, D. F. Swaab (Eds.), Handbook of Clinical Neurology, 3rd Series. Oxford: Elsevier. In press. 27. *Nater, U. M. & Heim, C. The role of stress in chronic fatigue syndrome (2010). In F.
Columbus (Ed.), Chronic Fatigue Syndrome. Hauppauge: Nova Science Publishers. In press. 28. *LaPrairie, J., Heim, C., Nemeroff, C. B. (2010). The neuroendocrine effects of early life
trauma. In R. Lanius & E. Vermetten (Eds.), The Effects of Early Life Trauma on Health and Disease. Cambridge University Press. 29. Heim, C., Miller, A.H. (2010). Depression. In U. Ehlert & R. Von Kaenel (Eds.),
Psychoendokrinologie und Psychoimmunologie. Berlin: Springer. 30. *Nater, U.M., Heim, C. (2010). Psychobiology of Functional Somatic Syndromes. Festschrift to
honor Boudewijn van Houdenhove. Im Druck. 31. Heim, C. (2011). Early-life Stress. Encyclopedia of Behavioral Medicine (Invited chapter). Im
32. Ditzen, B., Nater, U., Heim, C. (2011). Endocrine Challenge Tests. Encyclopedia of Behavioral
VERÖFFENTLICHTE ABSTRACTS
Heim, C., Ehlert, U., Hanker, J. P. & Hellhammer, D. H. (1995). Ein interdisziplinäres
Forschungsprojekt zur psychoendokrinologischen Untersuchung von Frauen mit chronischen
Unterbauchbeschwerden. Verhaltenstherapie, 5, A7.
Heim, C., Ehlert, U., Hanker, J. P., Hellhammer, D. H. (1995). Enhanced suppression of cortisol
following dexamethasone administration in chronic pelvic pain. European Journal of Oral
Sciences, 103, 35.
Hellhammer, D., Heim, C., Ehlert, U. & Hanker, J. P. (1996). The potential relevance of
hypocortisolism in bodily disorders: evidence in women suffering from chronic pelvic pain.
Psychosomatic Medicine, 58, 81.
Heim, C., Pisell, T. L., Pearce, B. D., & Miller, A. H. (1997). Discrimination of activation versus
down-regulation of the glucocorticoid receptor using a cytosolic binding assay combined with
a whole cell Western blot. Society for Neuroscience Abstracts, 27, 490.1.
Stout, S. C., Owens, M. J., Heim, C. & Nemeroff, C. B. (1997). Attenuation by venlafaxine of
stress effects on CRF systems and the HPA axis of rats. Society for Neuroscience Abstracts, 27,
424.5.
Heim, C., Graham, Y. P., Heit, S., Bonsall, R., Miller, A. H. & Nemeroff, C. B. (1998). Increased
reactivity of the hypothalamic-pituitary-adrenal axis to psychosocial stress in adult survivors
of childhood abuse. Society for Neuroscience Abstracts, 28, 201.12.
Heim, C., Graham, Y. P., Heit, S., Bonsall, B., Miller, A. H. & Nemeroff, C. B. (1998). Increased
sensitivity of the hypothalamic-pituitary-adrenal axis to psychosocial stress in adult survivors
of childhood abuse. Psychoneuroendocrinology, 23, S23.
Ehlert, U., Heim, C. & Hellhammer, D. H. (1998). Sind somatoforme Stoerungen mit einer
Dysregulation der Hypophysen-Nebennierenrinden-Achse assoziiert? Verhaltenstherapie, 7,
A7.
Heim, C., Graham, Y. P., Heit, S., Newport, D. J., Bonsall, R., Miller, A. H. & Nemeroff, C. B.
(1999). Pituitary-adrenal responses to the CRF stimulation test in adult survivors of childhood
abuse with and without depression. Society for Neuroscience Abstracts, 29, 358.1.
10. Hellhammer, D. H., Buske-Kirschbaum, A. & Heim, C. (2000). Stress induced disorders.
Neuropsychopharmacology, 23, S76. 11. Heim, C., Newport, D. J., Pearce, B. D., Wilcox, M. S., Nemeroff, C. B. & Miller, A. H. (2001).
Neuroendocrine and immune alterations in adult women after childhood abuse: implications for the pathophysiology of physical complaints. Society for Neuroscience Abstracts, 30, 412.15. 12. *Meinlschmidt, G., Hellhammer, D. H. & Heim, C. (2001). Erniedrigte Anstiege der
Cortisolkonzentration im Speichel nach dem Erwachen bei Erwachsenen mit frühen Verlusterlebnissen. Nervenheilkunde, 20, S135. 13. Heim, C., Newport, D. J., Miller, A. H. & Nemeroff, C. B. (2002). Neurobiological correlates of
child abuse in women. Stress, 5, S58. 14. *Meinlschmidt, G., Schmidt, I., Wingenfeld, K., Wagner, D., Hellhammer, D. H. & Heim, C.
(2002). Hypothalamic-pituitary-adrenal axis reactivity to physical stress in adult women with a history of child abuse. Stress, 5, S59. 15. *Meinlschmidt, G., Schmidt, I., Wingenfeld, K., Wagner, D., Schad, T., Braun, H. J., Sigmund, G. L., Pruessner, J., Hellhammer, D. H. & Heim, C. (2003). Adrenal gland volume in adult
women after sexual and physical abuse in childhood. Psychoneuroendocrinology.
16. *Wingenfeld, K., Schmidt, I., Meinlschmidt, G., Wagner, D., Hellhammer, D. H. & Heim, C.
(2003). Hypothalamic-pituitary-adrenal axis alterations in women with fibromyalgia syndrome. Psychoneuroendocrinology. 17. *Meinlschmidt, G., Schmidt, I., Wingenfeld, K., Wagner, D., Hellhammer, D. H. & Heim, C.
(2004). Decreased hypothalamic-pituitary-adrenal (HPA) axis reactivity after physical exerxise in adult women with a history of early life stress. Psychosomatic Medicine, 65 (Supplement 1), S45. 18. *Mletzko, T., Bruce, E. C., Fu, P., Le, N., Nemeroff, C. B., Manatunga, A., Heim, C. &
Musselman, D. L. (2005). Oxidative stress increases after mental stress. Biological Psychiatry, 57 (Supplement 8), 212S. 19. Rajeevan, M.S., Smith, A.R., Dimulescu, I., Vernon, S.D., Heim, C. & Reeves, W.C (2005).
Association of polymorphisms and haplotypes in the glucocorticoid receptor with chronic fatigue syndrome. American Society of Human Genetics Abstracts. 20. *Pace, T. W. W, Mletzko, T., Alagbe, O., Vogt, G. J., Hu, F., Miller, A. H., Bruce, E. C., Musselman, D. L., Nemeroff, C. B. & Heim, C. (2005). Indicators of innate immune system
activity in humans increase with psychosocial stressor challenge: Major depressives vs. non-
depressives. Society for Neuroscience Abstracts.
21. Nemeroff, C. B., Heim, C., Musselman, D. L., & Miller, A. H. (2006). Brain systems regulating
the organism’s response to stress: Preclinical and clinical studies. Neuropsychopharmacology, 30, S19. 22. Heim, C., Mletzko, T., Musselman, D. L. & Nemeroff, C. B. (2005). The combined
dexamethasone/CRF test in men with major depression: Role of childhood trauma. Neuropsychopharmacology, 30, S173:78. 23. Alagbe, O., Pace, T., Mletzko, T., Vogt, J., Nemeroff, C. B., Heim, C. & Miller, A. H. (2005).
Changes in natural killer cell function, inflammatory signaling, and plasma IL-6 production during acute stress in patients with major depression. Neuropsychopharmacology, 30, S264:145. 24. *Meinlschmidt, G., Schmidt, I., Wingenfeld, K., Wagner, D., Hellhammer, D. H., Heim, C.
(2005). Long-term biological changes after early adverse experiences in form of sexual and physical violence Verhaltenstherapie, 15(S1), 6. 25. *Meinlschmidt, G., Schmidt, I., Wingenfeld, K., Wagner, D., Hellhammer, D. H., Heim, C.
(2006). Altered female sex hormone effects on adrenocorticotropin secretion in women with adverse childhood experiences. Biologine Psichiatrija Ir Psichofarmakologija, 8, 33. 26. *Nater, U. M., Wagner, D., Jones, J. F., Unger, E. R., Reeves, W. C. & Heim, C. (2006). Coping
styles in cases with chronic fatigue syndrome identified from the general population in Wichita, Kansas. Psychosomatic Medicine, 68, A-101-102. 27. *Nater, U. M., Reeves, W. C. & Heim, C. (2006). Die Rolle von Stress beim Chronischen
Erschöpfungssyndrom. In G. W. Alpers, H. Krebs, A. Mühlberger, P. Weyers, P. Pauli (Hrsg.), Wissenschaftliche Beiträge zum 24. Symposium der Fachgruppe Klinische Psychologie & Psychotherapie (S. 23-24). Lengerich: Pabst. 28. Heim, C., Newport, D. J., Mletzko, T., Bonsall, R., Miller, A. H. & Nemeroff, C. B. (2006).
Increased cerebrospinal fluid CRF concentrations associated with childhood physical abuse in adult women. Society for Neuroscience Abstracts. 29. *Nater, U. M., Reeves, W. C. & Heim, C. (2006). The role of stress in chronic fatigue
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dysregulation in a population-based sample of cases with chronic fatigue syndrome, cases with insufficient fatigue, and non-fatigued controls. Psychosomatic Medicine, 69, 98-99. 31. *Nater, U. M., Jones, J. F., Unger, E. R., Reeves, W. C. & Heim, C. (2007). Basal endocrine and
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(2006). Enhanced psychological stress-induced IL-6 responses are associated with attenuated stress-induced cortisol responses in patients with major depression and increased early life stress. Brain, Behavior, and Immunity, 20, 54. 33. *Nater, U. M., Lin, J.-M., Maloney, E., Jones, J. F., C. L., Reeves, W. C. & Heim, C. (2008).
Psychiatrische Komorbidität bei Personen mit Chronischem Erschöpfungssyndrom. In P. Warschburger, W. Ihle, G. Esser (Hrsg.), Seelisch gesund von Anfang an. Potsdam: Universitätsverlag Potsdam. 34. *Nater, U. M., Reeves, W. C. & Heim, C. (2008). The relationship between stress and chronic
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