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Quality of life in alopecia areata: a study of 60 cases
M Dubois et al.
Quality of Life in Alopecia Areata
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Quality of Life in Alopecia Areata: A Study of 60 Cases
Journal of Investigative Dermatology (2010) 130, 2830–2833; published online 19 August 2010
skin disorders’’-specific Qol instru-
affected and symptoms the least one.
Qol for almost all the SF36 dimensions.
leisure activity, daily life, and physical
adherence to the Helsinki guidelines.
pathic urticaria, and atopic dermatitispatients; (ii) being less bothered totreatment-induced
Abbreviations: AA, alopecia areata; Qol, quality of life; SF36, short form 36
2830 Journal of Investigative Dermatology (2010), Volume 130
Table 1. Quality-of-life indicative comparisons between AA patients and other dermatological conditions, andFrench age- and sex-matched controls1
37.4±24.7 o0.001 23.8±21.8 o0.001 34.2±24.6 o0.001
0.145 36.2±20.4 o0.001 35.5±21.3 o0.001
49.3±25.2 o0.001 50.3±25.5 o0.001 50.1±25.5 o0.001
47.2±29.3 o0.001 36.7±28.1 o0.001 46.7±27.9 o0.001
Treatment restrictions 30.3±30.2 35.8±34.0
44.4±28.2 o0.001 61.4±23.7 o0.001 69.8±21.3 o0.001
Abbreviations: AA, alopecia areata; AD, atopic dermatitis; CU, chronic urticaria; HS, hidradenitis suppurativa; NF1, neurofibromatosis type 1; PSO,psoriasis; SF36, short form 36.
2SF36, 36 items, eight dimensions (range (0–100), 0 lowest and 100 highest level of Qol;
3VQ-Dermato, 28 items, seven domains and one overall score (range (0–100), 0 highest and 100 lowest level of Qol;
4Skindex, 29 items, three domains (range (0–100), 0 highest and 100 lowest level of Qol; Bold values Po0.05.
Table 2. Associations between VQ-Dermato dimension scores and global score, and sociodemographic/clinicalcharacteristics in 60 alopecia areata (AA) patients
M Dubois et al.
Quality of Life in Alopecia Areata
1Mean ± SD, P: P-value Mann–Whitney test.
2Spearman’s correlation coefficient, P: P-value Spearman’s test.
3Course of the disease was defined as ‘‘unstable’’ if there was alternation of worsening and improvement phases in the last 2 years, and ‘‘stable’’ otherwise.
4Severity 1: visual analog scale by reference to the cases of AA seen in daily practice; 0 ‘‘patient among the least affected’’ and 100 ‘‘patient among the mostaffected’’.
5Severity 2: visual analog scale by reference to the cases of all skin disorders seen in daily practice; 0 ‘‘patient among the least affected’’ and 100 ‘‘patientamong the most affected’’.
Bold values: Po0.05.
2832 Journal of Investigative Dermatology (2010), Volume 130
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role of psychological factors in alopecia
The authors state no conflict of interest.
areata and the impact of the disease on thequality of life. Int J Dermatol 43:352–6
Leplege A, Ecosse E, Pouchot J et al. (2001) MOS
ACKNOWLEDGMENTSThis work was supported by institutional grants
SF36 Questionnaire. Manual and Guidelines
from the PHRC 2005 (Program Hospitalier Recherche
for Scores’ Interpretation. Vernouillet: Estem,
Leplege A, Ecosse E, Verdier A et al. (1998)
tion, cultural adaptation and preliminary
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France). Adaptation and assessment of psycho-
1Department of Dermatology, Sainte-Marguerite
Hospital, Marseille, France; 2Department of
Wolkenstein P, Loundou A, Barrau K et al. (2007)
Clinical Research, Assistance Publique des
Quality of life impairment in hidradenitis
Hoˆpitaux de Marseille, Marseille, France;
suppurativa: a study of 61 cases. J Am Acad
EA3279 ‘‘Self-Perceived Health Assessment’’
Research Unit and Department of Public Health,
Wolkenstein P, Zeller J, Revuz J et al. (2001)
Nord Hospital, Universite´ de la Me´diterrane´e,
Quality-of-life impairment in neurofibroma-
tosis type 1: a cross-sectional study of 128
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