Deutsch Website, wo Sie Qualität und günstige https://medikamenterezeptfrei2014.com/ Viagra Lieferung weltweit erwerben.

Ein wenig Kopfschmerzen, aber schnell verging der Schmerz. Gefühle, die ich erlebte ein unvergessliches levitra kaufen Ehrlich gesagt nicht wirklich glauben, in der Kraft Viagra. Setzte nach der Anleitung. Das Ergebnis ist natürlich, sich selbst rechtfertigte.

G:\releases\2003\sales & results\q1\fy02.prn.pdf

Investor Relations
Novartis International AG
CH-4002 Basel
Switzerland
Karen J. Huebscher, Ph.D.
Tel + 41 61 324 84 33
Nafida Bendali
Tel + 41 61 324 35 14
Katharina Furrer
Tel + 41 61 324 53 16
Sabine Moravi Bottoli
Tel + 41 61 324 89 89
Silke Zentner
Tel +41 61 324 86 12
Fax +41 61 324 84 44Internet Address:http://www.novartis.com - Investor Relations Release -
Novartis meets full-year double-digit sales growth objective with strong
operating performance in 2002
Group sales up 11% in local currencies (2% in CHF) thanks to strong volume growth in Pharmaceuticals and GenericsPharmaceuticals consistently outperforms industry average in all major markets throughout 2002, delivering sales growth of 13% in local currencies (4% in CHF), driven by the cardiovascular and oncology franchisesDynamic growth in Generics (+25% in local currencies) produced by geographicGroup operating income climbs 8% on the back of strong top-line growth andNet income up 4% due to strong operating performance and a very satisfactory level of financial income amid adverse market conditionsEarnings per share rise 7% based on higher income and a reduction in the number of shares (share repurchase program)Free cash flow after dividend payment up 10%Switch to reporting in US dollars anticipated in the first quarter of 2003 Consolidated key figures
Full year
Operating income
Net income
Earnings per share/ADS
Number of employees
All USD figures are convenience translations of CHF into USD at a rate of 1.55. These translations should not be construed as representations that the CHF amounts could actually have been converted into the All product names appearing in italics are registered trademarks of the Novartis Group. Norvasc®, Baycol®, and Augmentin® are registered trademarks of Pfizer, Bayer and GlaxoSmithKline, respectively. Fourth quarter
USD m CHF m
Operating income
Net income
Earnings per share/ADS
Basel, 23 January 2003 – Commenting on the Group's 2002 full-year results published
today, Dr. Daniel Vasella, Chairman and CEO of Novartis, said: “We are pleased to report record results for the sixth consecutive year since Novartis was created. In 2002, virtually all of our businesses grew ahead of the market, gaining market share amid economic uncertainty and volatility. The continued strategic focusing of our business produced strong sales and operating performance. In our core Pharmaceuticals business, we strengthened our leadership, particularly in our cardiovascular and oncology franchises. Several innovative products were introduced, including Zelnorm, an innovative medicine for irritable bowel syndrome, and Elidel, a steroid-free cream for treating eczema. In addition, we gained further indications for Diovan, Zometa and Gleevec/Glivec, our breakthrough cancer drug that has brought new hope to patients and families. And, investing in the discovery of future medicines to sustain our growth, we created the Novartis Institute for Biomedical Research in Cambridge, Massachusetts.” Group sales up 11% to CHF 32.4 billion (USD 20.9 billion)
Group sales grew 11% in local currencies (2% in CHF), driven by strong volume increases, especially in Pharmaceuticals and Generics. Ten percentage points of sales growth came from volume expansion and a further 1 percentage point from price increases. This more than offset the negative currency impact of 9 percentage points due to the prevailing strength of the Swiss franc, which squeezed sales growth in CHF to 2%. In US dollars, Group sales soared 11% to USD 20.9 billion, reflecting increases in local currencies of 13% in Pharmaceuticals and 25% in Generics, the main contributors.
Operating income rises 8% to CHF 7.9 billion (USD 5.1 billion)
Productivity gains and improvements in the product mix led to a reduction in the cost of goods sold. A reduction was also achieved in General & Administration costs. On the other hand, investments were stepped up in line with sales both in Marketing & Distribution, to support product launches, and in Research & Development. As a result, operating income increased overproportionately, climbing 8% in Swiss francs to CHF 7.9 billion (USD 5.1 billion), with a substantial gain in operating margin of 1.3 percentage points to 24.3%.
Net income up 4% to CHF 7.3 billion (USD 4.7 billion)
The strong operating performance together with an attractive level of net financial income (CHF 949 million; USD 612 million), achieved in a difficult financial environment, lifted full-year net income 4% in Swiss francs to CHF 7.3 billion (USD 4.7 billion).
On the basis of the good 2002 performance, a dividend increase of 6% to CHF 0.95 per share will be proposed to the shareholders' AGM.
Outlook 2003 (barring any unforeseen events)
Novartis expects dynamic sales growth to continue in 2003 as it continues to focus on its core Pharmaceuticals business and key therapeutic areas.
An aggressive investment strategy will be pursued to sustain high-level growth.
Pharmaceutical Research investments are projected to increase by more than 20% in 2003 and overproportionately to sales. This is expected to lead to a decrease in Pharmaceuticals’ Despite the higher investments in Research and a lower anticipated level of financial income due to the challenging economic environment, both operating and net income are expected to exceed the previous year’s levels, barring any unforeseen events.
As previously announced, the Group foresees reporting its financial results in US dollars beginning with the first quarter results in 2003. This reflects the continued increasing strategic importance of the US to Novartis’ business.
Sales by division and business unit
Full year

Pharmaceuticals
Consumer Health (ongoing)
Divested Health & Functional Food activities Consumer Health
Fourth quarter
Pharmaceuticals
Consumer Health (ongoing)
Divested Health & Functional Food activities Consumer Health
Sales in 2001 have been reduced by CHF 129 million (USD 83 million) in OTC, CHF 50 million (USD 32 million) in Medical Nutrition and CHF 216 million (USD 139 million) in Infant & Baby, with a corresponding reduction in Marketing & Distribution expenses, to reflect a change in the classification of certain sales incentives and discounts to retailers.
Operating income by division and business unit
Full year

Pharmaceuticals
Consumer Health
(ongoing)
Divested Health &
Functional Food
activities
Consumer Health
Fourth quarter
Pharmaceuticals
Consumer Health
(ongoing)
Divested Health &
Functional Food
activities
Consumer Health
Pharmaceuticals Division
The core Pharmaceuticals business posted double-digit sales growth throughout the year, gaining total market share in 2002. Overall, sales grew 13% (4% in CHF) to CHF 21.0 billion (USD 13.6 billion) over the full year and 11% (1% in CHF) in the fourth quarter, with dynamic momentum in the key cardiovascular and oncology businesses, where Diovan, Lotrel, Lescol, Gleevec/Glivec, Zometa and Sandostatin were the main growth The introduction of Elidel and Zelnorm/Zelmac, a new strength of Lotrel, new indications for Zometa, Diovan, Visudyne, and Gleevec/Glivec and the increasing popularity of Lescol all contributed to lifting sales. In 2002, Novartis again achieved one of the highest numbers of key-market approvals in the pharmaceutical industry, with 11 registrations and 18 submissions in the US, EU and Japan.
In the key US market, sales grew 12%. Double-digit sales growth was also achieved in all other major regions led by Latin America (LATAM; +17%) and Japan (+15%) despite government mandated price decreases. In Europe, strong volume gains in Spain and France offset the effects of pricing pressures in several countries, mandatory generic substitution in Germany, and the effects of parallel imports both in Germany and the UK.
Operating income
Pharmaceuticals’ operating income climbed 6% to CHF 6.0 billion (USD 3.9 billion). The cost of goods sold improved 1.2 percentage points of sales owing to product mix changes and productivity gains. Marketing & Distribution investments increased as a percentage of sales to support the US launches of Elidel and Zelnorm. Implementation of the new research strategy and the establishment of the new Cambridge facility to power future innovation led to a 4% increase in Research & Development investments, which were Highlights
Primary Care
In 2002, Diovan (+49%, US: +40%; hypertension) became Novartis’ best selling product
ever, further extending its category leadership in the US to more than 35.5% of total
prescriptions at the end of November. In the US, wholesaler inventories increased in the first half and returned to normal levels by the fourth quarter, which is reflected in the quarterly sales figures. Total prescriptions, however, grew consistently above 40% throughout the year, underlining the steady growth in demand for Diovan. Backed by the Val-HeFT study, Diovan became the first and only drug of its kind to be approved by the FDA for treating heart failure patients who are intolerant of ACE inhibitors. Novartis is seeking similar approvals in Europe and other markets. To complement the broad choice and flexibility for patients and physicians, a new higher dose (160/25) formulation of Co- Diovan was launched in the US in May.
Lotrel (US: +35%; hypertension) also extended its share of new prescriptions, supported by
its positioning as the “go to” agent after ACE failure and by data from the LOGIC study
showing that patients switched from Norvasc® experienced better blood-pressure control with less edema. A new dosage strength was launched in mid year and was well received by physicians and patients, reflecting the fact that 90% of Lotrel patients achieve their blood-pressure goal. Further new strengths were filed in December for FDA approval.
Lescol (+18%, US: +13%; cholesterol reduction) sales grew dynamically in Europe and
strongly in other regions, reflecting the drug’s particularly favorable risk/benefit profile and
convenient XL extended-release formulation. US sales continued to grow in the fourth quarter, but less dramatically than in the comparative period of 2001, when patients switched to Lescol after the withdrawal of Baycol®. Following the publication of data showing that Lescol reduced the risk of serious cardiac events after surgery to unblock coronary arteries, a new indication in angioplasty patients was filed for regulatory Lamisil (+4%, US: –3%; fungal infections) sales picked up towards the end of the year
mainly in the US. Whilst the onychomycosis market segment is declining, Lamisil extended
its share of both total and new prescriptions in the US oral antifungal segment to more than Elidel (eczema) was launched in 13 countries, including the US, and completed the mutual
recognition procedure in Europe. Sales reached CHF 148 million (USD 95 million). Within
just six months, this highly effective, non-steroid cream became the number-one branded prescription treatment for eczema in the US, where it has now captured 8.6% of new prescriptions. Following its first European launch, in Denmark, Elidel captured a 9% value share of its segment within 10 weeks of launch.
Exelon (+26%, US: +28%; Alzheimer’s disease) posted good sales growth and captured a
further share both of new and total prescriptions in the US. New marketing initiatives are
under way to counter increased competition in its fast-growing segment. Studies revealed that Exelon inhibits an additional enzyme (butyrylcholinesterase) that contributes to neurological dysfunction in Alzheimer’s disease. As a result, an expanded labeling was approved in Europe to include the product’s unique dual inhibition properties. An application to the FDA for the expanded labeling was recently filed.
Trileptal (+91%, US: +111%; epilepsy) continued to post good sales growth and
outperform its segment. The increasing use as monotherapy for partial seizures, together
with launches in Canada and Australia, and the publication of new data in October, all contributed to the product’s success.
Zelnorm/Zelmac (constipation-prone irritable bowel syndrome) has now been launched in
28 countries and sales reached CHF 70 million (USD 45 million). After just three months on
the US market, physicians are conservative in recognizing and diagnosing appropriate patients for Zelnorm. Novartis has initiated several programs to improve awareness and Oncology
Novartis Oncology gained further market share and posted strong sales growth of 28% in local currencies (+19% in CHF). Novartis is one of the fastest growing top oncology Gleevec/Glivec, (+303%, US: +103%;) for chronic myeloid leukemia (CML) and
gastrointestinal stromal tumors (GIST), continued to bring benefits to thousands of patients
in more than 80 countries. Exceeding expectations, twelve-month sales topped CHF 953 million (USD 615 million), making it Novartis’ fifth biggest product. Gleevec/Glivec has now been approved as first-line treatment in the US, EU and Switzerland, and major progress has been achieved on reimbursement, especially in the UK, Australia and New Zometa (bone metastases and complications of a broad range of cancers) achieved sales of
CHF 758 million (USD 489 million), making it the most prescribed intravenous
bisphosphonate for bone metastases. More potent and convenient than Aredia, Zometa has gained EU and US approvals for a broader range of cancer settings.
Sandostatin (acromegaly and carcinoid syndrome) continued to post substantial double-
digit growth, with sales up 23% (US: +39%) to CHF 943 million (USD 608 million).
Growth was driven by continued market penetration of the convenient, long-acting, once-a- Femara, the first-line therapy for advanced breast cancer in postmenopausal women,
posted a 37% (US: +55%) rise in sales to CHF 271 million (USD 175 million).
Ophthalmics
Ophthalmics’ sales rose 7% in local currencies (–1% in CHF), driven by Visudyne. Demand for other Ophthalmics brands increased although sales reflect a reduction in wholesaler Visudyne (+27%, US: +19%; treatment in macular degeneration) sales reached CHF 443
million (USD 286 million) as growth continued in all regions. Visudyne therapy has now
been approved in more than 65 countries for its main indication and in more than 45, including the EU, US and Canada, for additional indications. EU approval for use in occult age-related macular degeneration was granted in August, while positive data from four- year studies were presented in October, underlining the long-term benefits of Visudyne Transplantation
Full-year sales decreased 4% in local currencies (–11% in CHF) as generic and branded competitor products continued to have only a limited impact on the Neoral franchise. This reflects the fact that Neoral is a critical dose drug and the importance physicians attach to avoiding fluctuations in drug concentrations in patients who are stable and doing well on Sales of Neoral/Sandimmun (–5%; US: –12%), the cornerstone drug for immuno-
suppression, were underpinned by market share gains in Japan, which partly offset price
pressures, branded competition and generic erosion in other regions. Sandimmun, which contributes approximately 25% of the combined Neoral/Sandimmun franchise sales in the US, contended with a new generic competitor there in the third quarter. Nevertheless, after 31 months, generic competitors have eroded only 33% of Novartis’ total US cyclosporin franchise, setting a benchmark industry-wide.
Simulect, the induction immunosuppressant designed to complement Neoral, posted a 21%
rise in sales (US: +4%) following its successful launch in Japan and continued market
segment share gains from established competitor brands in most regions.
Myfortic gained first approvals in Switzerland, Brazil, India, and Australia for preventing
organ rejection in kidney transplantation.
Mature Products
On a comparable basis, the mature brands continued to report only a modest decline in overall sales as a result of focused investments on selected key products and markets.
Voltaren (-3%, US: –18%; anti-inflammatory) continued to compete well against generics
and the COX-2 inhibitor class of drugs.
Cibacen/Cibadrex (antihypertensive) continued to deliver positive results as sales climbed
9% (US: 14%), mainly as a result of renewed external field-force support in the US.
Pipeline update
Prexige, (arthritis and pain), Novartis’ COX-2 selective inhibitor, was filed in the US and
EU in November as a 200 mg/day dose, for long-term use, and a 400 mg/day short-term
dose. The TARGET trial is expected to provide information on the safety and tolerability of the high dose in long-term therapy. Final results are anticipated in mid 2004. In the rheumatoid arthritis indication, Novartis has started another pivotal trial, which will be An amendment to the marketing application for Xolair (asthma treatment in development
under an agreement between Novartis Pharma AG, Genentech, Inc. and Tanox, Inc.) was
The Foradil Certihaler, a new-generation inhaler system for asthma patients, was
submitted to regulatory authorities in the US and EU in December.
Starlix (diabetes) was also filed in the US in December for use in combination with
rosiglitazone, a commonly used oral antidiabetic.
Certican, a novel drug that targets primary causes of chronic rejection in heart and kidney
transplantation, was submitted for marketing approval in the EU in July and in the US in
Comtan (Parkinson’s disease) was filed in the US in August for approval as a combination
product with levodopa and carbidopa.
Clinical development (Phase II) programs were initiated for Zoledronic acid in the new
indication of rheumatoid arthritis, RAD001 in rheumatoid arthritis, and SMC021, an oral
formulation of Miacalcic (osteoporosis). FTY720A, the first lymphocyte homing agent that
prevents acute rejection of transplants, is due to enter Phase III of clinical development in
the first half of 2003. The Oncology projects ICL670 (chronic iron overload) and PTK787
(colorectal cancer) also moved into Phase III, whilst first positive clinical results from a
pilot trial were reported for PKC412 in advanced phase acute myeloid leukemia.
Novartis is evaluating its options regarding the continued development of Iloperidone
(schizophrenia), a project with Titan Pharmaceuticals, including the possibility of sublicensing the compound to another company.
LBL752, an investigational compound for diabetes, has been returned to the licensor, Dr.
Reddy's Laboratories, whilst potential backup compounds continue to be evaluated as part Consumer Health Division
Generics
Generics posted dynamic sales growth of 25% in local currencies (15% in CHF) to CHF 2.8 billion (USD 1.8 billion), driven by increased volumes, while prices eroded by 1%.
Acquired businesses added approximately 2% to sales growth. The overall performance was led by the US and Europe, supported by new product launches and expansion into new The retail generics franchise with finished forms achieved exceptionally strong gains with full-year sales climbing 35%, driven by a strong US performance and new product launches, in particular AmoxC, Geneva’s generic version of the anti-infective Augmentin®.
Sales growth was also fuelled by other new products, including mefloquine (malaria), nabumetone (inflammation), metformin (diabetes), fluoxetine (depression), lisinopril and lisinopril HCTZ (hypertension). In Europe, sales grew dynamically, especially in France, Italy and the Netherlands, owing to the success of newly launched products such as the The industrial generics franchise edged up 3% in local currencies from the previous year’s high level of sales, driven by continued strong sales of bulk antibiotics and the penicillin In November, Generics successfully completed its friendly takeover of Lek, Slovenia’s leading drug-maker, for approximately CHF 1.3 billion (USD 0.8 billion). The acquisition opens up a leading position for Generics in the fast-growing Eastern European market.
Operating income
Operating income soared 44% to CHF 406 million (USD 262 million), fuelled by volume growth, productivity gains and new product launches. Although regional sales forces were expanded and new markets entered, Marketing & Distribution expenses were significantly reduced as a percentage of sales, owing to strong topline growth. Research & Development investments increased 27%, mainly due to product developments and funding for the R&D center in Vienna. Legal fees and provisions for defending patent challenges led to a 38% increase in General & Administration expenses. The dynamic sales trend, improvement of gross margin, and the reduction in functional costs as a proportion of sales lifted the operating margin 3 percentage points to 14.5%.
Sales of OTC (over-the-counter) medicines reached CHF 2.4 billion (USD 1.5 billion), one percent off the previous year’s level in local currencies (–7% in CHF).
Excluding terminated, acquired and transferred businesses, underlying sales grew 3% in local currencies, driven by the key brands Lamisil (antifungal), Voltaren (analgesic), Otrivin (nasal decongestant) and Nicotinell/Habitrol (smoking cessation). The growth of these products compensated for the weak cough and cold season in North America and a drop in Calcium Sandoz sales in Europe and Mexico.
Operating income
Operating income dropped 17% to CHF 374 million (USD 241 million), largely as a result of expenses due to the reorganization of the Consumer Health Division and the OTC Business Unit, partially offset by productivity gains and product-mix improvements. In addition, Marketing & Distribution expenses fell, mainly due to the discontinuation of the KAO agreement in Japan. The operating margin declined 1.9 percentage points to 15.9%.
Animal Health
Sales were up 10% in local currencies (1% in CHF) to CHF 0.97 billion (USD 0.63 billion), driven by double-digit growth in the LATAM region and the US, where the vaccine businesses acquired in January were the main contributors. Overall, acquisitions contributed approximately 6 percentage points to sales growth.
The companion animal franchise was driven by strong sales of Interceptor (worm treatment) and Fortekor (heart/kidney failure), complemented by a number of new launches in key markets. The product range was strengthened by the addition of Milbemax (intestinal parasites in cats and dogs), as well as Atopica (atopic dermatitis in dogs) and Deramaxx (pain control in dogs), which both marked entries into new therapeutic areas.
Sales in the farm animal franchise grew dynamically, driven by the therapeutic anti- infectives, a strong performance in the LATAM region and the recovery in the UK from the foot and mouth epidemic of 2001. In Australia, prolonged drought severely reduced livestock numbers, which could affect the regional business beyond 2002.
The acquisition of Grand Labs and Immtech in the US boosted the vaccines and aquahealth franchise, which posted a strong rise in sales and now contributes 8% of the Business Unit’s Operating income
Operating income rose 4% to CHF 144 million (USD 93 million), leading to an operating margin of 14.8%, in spite of acquisition-related costs and the exchange rate effects. As a percentage of sales, Research & Development investments were maintained at their prior year levels and efficiency improvements in Marketing & Distribution more than absorbed Medical Nutrition (including Nutrition & Santé)
Medical Nutrition and Nutrition & Santé sales grew 4% in local currencies (–1% in CHF) to CHF 1.1 billion (USD 0.7 billion).
Medical Nutrition posted mid single-digit growth as double-digit sales growth in Europe was offset by the decrease in wholesaler inventory levels in the US. Sales continue to be led by the strong performance of Enteral Nutrition (Isosource and Novasource). Additional sales impetus came from the Medical Food franchise (Resource), which continued to benefit from the expansion of the home-care channel.
The Health Food & Slimming and Sports Nutrition businesses have been reorganized into a stand-alone unit, Nutrition & Santé, to optimize their business potential and to prepare for Operating income
Full-year operating income amounted to CHF 6 million (USD 4 million) compared with CHF 87 million (USD 56 million) in 2001, and was impacted by divestment-related restructuring charges of CHF 40 million (USD 26 million) and a one-time provision for potential value-added, tax charges in Germany. Excluding the exceptional items, which totaled CHF 66 million (USD 43 million), the operating income would have been CHF 72 million (USD 46 million), leading to an operating margin of 6.5%.
Infant & Baby
Infant & Baby sales grew above the industry average, climbing 3% in local currencies (– 7% in CHF) to CHF 2.1 billion (USD 1.3 billion). The main contributor was Gerber, which increased market share in the US by almost 3 percentage points compared with 2001. Sales growth was spurred by innovations in the Juice, Graduates, and Tender Harvest lines and the outstanding success of Lil’ Entrées, a new line of microwavable convenience trays targeted at the rapidly-growing toddler segment. Gerber’s revenues from this segment were Innovations, such as convenient spill-proof cups, helped the Baby Care franchise to achieve a record share of its market segment, despite intense competition. Meanwhile, Gerber Wellness posted strong sales growth of 7%, lifted by the successful relaunch of its infant Operating income
Operating income dropped 9% to CHF 355 million (USD 229 million), owing to one-off goodwill impairment charges of CHF 39 million. As a result, the operating margin fell 0.3 percentage points to 17.1%. Excluding these exceptional charges, operating margin would CIBA Vision
CIBA Vision sales increased 6% in local currencies (–1% in CHF) to CHF 1.8 billion (USD 1.1 billion), driven by the high volume lens business, which outpaced the market and more than compensated for the foreseen decline in specialty lenses and lens care products.
Focus DAILIES and NIGHT & DAY contact lenses continued to perform dynamically, leading their respective categories of daily disposables and continuous wear. FreshLook colored lenses remained strong category leaders, underpinned by growing demand and the launch in several countries of FreshLook Radiance, which gained FDA approval in December. Focus DAILIES Toric, the world's first and only daily disposable contact lens for the correction of astigmatism, was launched in several European countries and is in the process of being introduced in the US.
The lens care franchise continued to compete in a shrinking market mainly in the US. Sales declined, but were underpinned by other regions and the rollout of FreshLook Care in The ophthalmic surgical business was lifted by several innovative products including VisThesia, a combination viscoelastic gel and anesthetic, intended to help shorten cataract surgeries, Vivarte PRESBYOPIC phakic refractive lens, and an improved convenient injector system for the PRL phakic refractive lens. In August, CIBA Vision obtained exclusive marketing rights in the US and Canada for the Ex-PRESS mini glaucoma shunt, an innovative and minimally invasive surgical treatment for glaucoma.
Operating income
Full-year operating income rose 5% to CHF 183 million (USD 118 million). Investments in Marketing & Distribution were increased to power new launches and advertising campaigns mainly in the US. Research & Development investments increased to support the development of new products and lens production technology. The fact that costs in 2001 related to the integration of Wesley Jessen did not recur in 2002, combined with synergies from the integration and a stability in cost of goods sold, all contributed to a lift in operating margin from 9.7% to 10.4%.
Divested Health & Functional Food Activities
In November, the Food & Beverage business (including the Ovaltine, Caotina and Lacovo brands) was successfully divested to Associated British Foods for CHF 402 million (USD 259 million). Sales up to divestment totaled CHF 325 million (USD 210 million).
The operating income comprises a divestment gain of CHF 205 million (USD 132 million) arising on the divestment of the Food & Beverage business and the normal operating income from these activities of CHF 40 million (USD 26 million), offset by CHF 29 million (USD 19 million) of goodwill impairment charges in connection with this divestment.
Corporate
Corporate income, net
This includes the costs of corporate management, income resulting from charging share and share option plan costs to the operating companies, and pension income. Net corporate income increased CHF 94 million (USD 61 million) in comparison with the previous year.
Income from associated companies
In total, associated companies contributed an expense of CHF 10 million (USD 6 million).
Novartis' 42% stake in Chiron Corporation contributed CHF 167 million (USD 108 In the course of 2002, the Group acquired, as a long-term financial investment, a further 11.4% of the voting shares of Roche Holding AG for CHF 2.9 billion (USD 1.9 billion), bringing its total stake to 32.7% of the voting shares or 6.2% of the total shares and equity Financial income, net
A lower but nevertheless attractive level of financial income net, totaling CHF 949 million (USD 612 million), was generated in a difficult environment due to good currency management and equity strategies. Gross financial income of CHF 1144 million (USD 738 million), including net income on options and forward contracts and deducting other financial expense, was CHF 408 million (USD 263 million) lower than in 2001 because the average level of liquidity and interest rates were substantially reduced in 2002. This was partially offset by lower interest expense of CHF 301 million (USD 194 million) compared with CHF 367 million in 2001, and by net currency hedging gains of CHF 106 million (USD 68 million). The net currency gain was due to currency hedging gains of CHF 380 million (USD 245 million), mainly from US dollar and Japanese yen positions, partially offset by Strong balance sheet
Novartis maintained the strength of its balance sheet at 31 December 2002 and continues to be rated AAA by Standard & Poors and Moody's.
In July, a third share buy-back program was initiated to repurchase shares via a second trading line on the SWX Swiss Exchange for up to a total of CHF 4 billion. On 31 December, approximately 24.6 million shares had been repurchased for a total of CHF 1.5 billion. If approved by the shareholders, the repurchased shares will be cancelled in order to reduce the Group’s issued share capital. In addition, a net 55.4 million shares were acquired on the first trading line for CHF 3.6 billion. This amount was offset by CHF 0.3 billion as a result of share transactions for an acquisition and for the conversion of debt to equities.
On the other hand, the Group was able to benefit from its AAA rating to increase liquidity reserves by issuing additional long-term debt at relatively low rates. In November, a highly successful EUR 1 billion, five-year, bond issue was launched and the proceeds were swapped into Yen at an all-in fixed rate of 0.23% per annum.
The Group’s equity decreased CHF 2.6 billion to CHF 39.7 billion at 31 December 2002 compared with the year end 2001, as net income (CHF 7.3 billion) only partially offset dividend payments (CHF 2.3 billion), the acquisition of treasury shares (CHF 4.8 billion), translation losses (CHF 1.5 billion) and a reduction of CHF 1.3 billion, principally due to a reduction in the fair value reserve for marketable securities and for cash-flow hedges.
Total financial debts fell CHF 0.9 billion on account of the conversion of CHF 1.2 billion of convertible debt and a reduction of other short-term debt which was partially offset by the EUR 1.0 billion straight bond issue. As a result of this, the year-end debt/equity ratio fell from 0.21:1 in 2001 to 0.20:1 in 2002.
Double-digit increase in cash flow
The cash flow from operating activities increased 11% (CHF 820 million) to CHF 8.2 billion mainly as result of higher net income, coupled with the fact that a higher portion of expenses were non-cash items. Depreciation, amortization and impairments charges increased by CHF 0.3 billion to CHF 2.1 billion. Although the total tax charge increased by CHF 50 million, taxes paid were CHF 181 million lower than in 2001.
Cash outflow due to investing activities was CHF 4.5 billion, only marginally below 2001.
CHF 4.2 billion were spent to increase the strategic investment in Roche and for the acquisition of Lek. The investment in tangible fixed assets accounted for CHF 1.7 billion.
The net proceeds from the sale of marketable securities totaled CHF 0.7 billion and the proceeds from the sale of the Food & Beverage business was CHF 0.4 billion.
Cash flow used for financing activities was CHF 6.6 billion. CHF 5.1 billion was spent on the acquisition of treasury shares and CHF 2.3 billion on dividend payments. The issue of a EUR 1 billion bond and the repayment of loans led to a net inflow of CHF 0.8 billion.
The free cash flow, excluding the impact of the acquisitions of the Roche stake, Lek and marketing product rights increased 10% from CHF 4.1 billion to CHF 4.5 billion.
Overall, liquidity (cash, cash equivalents and marketable securities including financial derivatives) amounted to CHF 17.6 billion at 31 December 2002. After deducting financial debt net liquidity thus remains high at CHF 9.8 billion.
Annual Report
Details of Novartis 2002 performance, including Human Resources, Corporate Governance, Health Safety and Environmental Protection reports can be found in the Group's Annual Report, published today on http://www.novartis.com.
This release contains certain “forward-looking statements”, relating to the Group’s business, which can be identified by the use of forward-looking terminology such as “foreseen”, “will”, “Outlook”, “foresees”, “expected to”, “intends”, or similar expressions, or express or implied discussions regarding potential future sales of existing products, potential new products or potential new indications for existing products, or by other discussions of strategy, plans or intentions. Such statements reflect the current views of the Group with respect to future events and are subject to certain risks, uncertainties and assumptions. There can be no guarantee that existing products will reach any particular sales levels, or that any new products will be approved for sale in any market, or that any new indications will be approved for existing products in any market. In particular, management's expectations could be affected by, among other things, new clinical data; unexpected clinical trial results; unexpected regulatory actions or delays or government regulation generally; the company's ability to obtain or maintain patent or other proprietary intellectual property protection; competition in general; and other risks and factors referred to in the Company's current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.
Reporting Dates in 2003
Consolidated income statements (audited)
Full year
Total sales
Gross profit
Operating income
Income before taxes and
minority interests
Net income
Fourth quarter (unaudited)
Total sales
Gross profit
Operating income
Income before taxes and
minority interests
Net income
1 Due to new accounting rules, 2001 sales have been restated to reflect a change in the classification ofcertain sales incentives and discounts to retailers. This restatement amounted to a sales reduction of CHF395 million in 2001 (CHF 95 million in the fourth quarter) with a corresponding reduction in Marketing &Distribution expenses. All USD figures are convenience translations of CHF into USD at a rate of 1.55. These translations should notbe construed as representations that the CHF amounts could actually have been converted into the USDamounts indicated. Condensed consolidated balance sheets (audited)
Assets
Total long-term assets

Current assets
Total current assets
Total assets
Equity and liabilities
Total equity

Long-term liabilities (including minority
Total long-term liabilities
Short-term liabilities
Total short-term liabilities
Total liabilities
Total equity and liabilities
Condensed consolidated cash flow statements and change in liquidity
(audited)
Net income
Depreciation, amortization and impairments Net income adjusted for non-cash items
Cash flow before working capital and
provision changes
Cash flow from operating activities
Cash flow used for investing activities
Cash flow used for financing activities
Change in cash and cash equivalents
financial debt and financial derivatives Change in net liquidity
Net liquidity
Free cash flow
Consolidated changes in equity (audited)
Consolidated equity at 1 January
Consolidated equity at 31 December
Share information
Average number of shares outstanding (million) 31 Dec. 2002
Principal currency translation rates
Average rates
Period-end rates
31 Dec. 2002
Notes to the financial report for the year ended 31 December 2002
1. Basis of preparation
The 2002 Annual Report has been prepared in accordance with International Accounting
Standards.
2. Changes in the scope of consolidation
The following significant changes were made during the years to 31 December 2002 and
2001:
Animal Health
In January, the Business Unit completed the acquisition of two US farm animal vaccine
companies, Grand Laboratories Inc., Iowa and ImmTech Biologies Inc., Kansas. The
combined 2001 revenues were approximately CHF 55 million and the combined purchase
price is a minimum of CHF 168 million of which CHF 133 million was settled in Novartis
American Depositary Shares. The final purchase price may increase depending on whether
certain future sales and other targets are met.
Medical Nutrition – including Health & Functional Food (H&FF)
The sale of the Food & Beverage portion of the H&FF businesses to Associated British
Foods for CHF 402 million was completed in November. The divested businesses' sales
were CHF 325 million in 2002.
Generics
In November, 99% of the shares of Lek, Slovenia’s leading drug-maker, were acquired for
approximately CHF 1.3 billion. The acquisition opens up a leading position for Generics in
the fast growing Eastern Europe market. Only a provisional balance sheet has been
included in the 31 December 2002 consolidated financial statements. Lek sales will be
consolidated as of 1 January 2003.
Corporate
In the course of 2002, the Group increased its stake in Roche Holding AG voting shares by
11.4%, bringing its overall stake to 32.7%. In total at 31 December 2002 the Group owned
6.2% of Roche's total shares and equity securities.
Generics
In January, Generics acquired the generic business line in the USA of Apothecon Inc. from
Bristol Myers Squibb, and acquired BASF's European generics activities. In April, Generics
acquired Labinca SA, Buenos Aires, Argentina and Lagap Pharmaceuticals Ltd., UK.
Corporate
During 2001, the Group acquired 21.3% of the voting shares of Roche Holding AG, which
represented 4.0% of its total shares and equity securities.
3. Significant differences between IAS and United States Generally Accepted
Accounting Principles
The Group's consolidated financial statements have been prepared in accordance with IAS,which, as applied by the Group, differs in certain significant respects from US GAAP. Theeffects of the application of US GAAP to net income and equity are set out in the tablesbelow.
Net income under IAS
Purchase accounting: IAS goodwill amortization Available-for-sale securities and derivative financial Consolidation of share-based compensation foundations Deferred tax effect on US GAAP adjustments Net income under US GAAP
31 Dec. 2002
Equity under IAS
Purchase accounting: IAS goodwill amortization Consolidation of share-based compensation foundations Deferred tax effect on US GAAP adjustments Equity under US GAAP
Basic earnings per share under US GAAP (CHF) Diluted earnings per share under US GAAP (CHF) Supplementary tables: 2002 – Sales of top twenty pharmaceutical products
Rest of world
Therapeutic area
currencies
currencies
currencies
Diovan/Co-Diovan
Neoral/Sandimmun
Lamisil (group)
Lotrel
Gleevec/Glivec
Sandostatin (group)
Voltaren (group)
Lescol
Zometa
Cibacen/Lotensin/Cibadrex
Top ten products total
Miacalcic
Tegretol (incl. CR/XR)
Leponex/Clozaril
Exelon
Visudyne
HRT range
Trileptal
Aredia
Foradil
Famvir*
Top twenty products total
Rest of portfolio
* 2001 restated because of transfers to other sectorsN/A - not applicable as no or insignificant prior year salesAll USD figures are convenience translations of CHF into USD at a rate of 1.55. These translations should not be construed as representations that the CHF amounts could actually have beenconverted into the USD amounts indicated. Supplementary tables: Fourth quarter 2002 – Sales of top twenty pharmaceutical products
Rest of world
Therapeutic area
currencies
currencies
currencies
Diovan/Co-Diovan
Neoral/Sandimmun
Lamisil (group)
Lotrel
Gleevec/Glivec
Sandostatin (group)
Voltaren (group)
Lescol
Zometa
Cibacen/Lotensin/Cibadrex
Top ten products total
Miacalcic
Tegretol (incl. CR/XR)
Leponex/Clozaril
Exelon
Visudyne
HRT range
Trileptal
Aredia
Foradil
Famvir*
Top twenty products total
Rest of portfolio
* 2001 restated because of transfers to other sectorsN/A - not applicable as no or insignificant prior year salesAll USD figures are convenience translations of CHF into USD at a rate of 1.55. These translations should not be construed as representations that the CHF amounts could actually have beenconverted into the USD amounts indicated. Supplementary tables: Sales by region
% of total
% of total
Pharmaceuticals
US
Generics
US
Animal Health
US
Medical
Nutrition
1
US
Infant & Baby
US
CIBA Vision
US
Consumer Health
US
1 Including Nutrition & Santé and divested activities

Source: http://glivec.jinbo.net/maybbs/pds/glibec/data/press_release_full_year_results_2002.pdf

Microsoft word - mini dv d00

MINI DV D001 Thank you for purchasing MINI DV—D001. It has adopted unique ultra-portable design, which makes it apply to every area. MINI DV—D001 brings more convenience, safety and funs to your I Characters of Product It has small contour design, which does UV spray finishing for the whole body. It is very fashionable and wearable and matches with all kinds of portable tools. Su

school.lisk.in

To find a code that satisfies C = C⊥, C has to be a [2k, k]-code satisfyingIn particular, ∀u ∈ C : u · u = 0, therefore every codeword in C has even parity. This alsoimplies that all codewords have to differ in even number of zeros. Next, let me claim that we can consider only bases with codewords containing exactlytwo ones (instead of considering bases with four ones; zero and six are u

Copyright © 2010-2014 Health Drug Pdf