2ND G-I-N CONFERENCE 2004
What sources of information are GPs using for prescribing?
Speaker: Bruce Arroll, University of Auckland, New Zealand Additional authors: F Goodyear-Smith, D Patrick, J Harrison and N Kerse.; University of Auckland, (This study was funded by the Ministry of Health, but the opinions are those of the authors.)
The general practitioners information resources and prescribing decisions project was undertaken
1. to establish sources GPs use to inform themselves on prescribing decisions.
2. to describe how GPs keep their information up to date.
3. to establish what other factors influence GPs prescribing decisions.
A random national sample of 200 General Practitioners within New Zealand was drawn from
MediMedia, Initial contact was made with a GP via fax, sending a cover letter and Participant
Information Sheet (PIS). The actual interview was undertaken by a non clinical interviewer using
Computer Assisted Telephone Interviewing (CATI) techniques.
Data was collected from 117 GPs throughout New Zealand. The most commonly used source of
prescribing information was the MIMs/NewEthicals drug information book and most GPs felt this was
very useful. It was the most commonly used source for drug dosage, drug interaction, and adverse
reactions. Other sources were accessed for information about complex prescribing situations such as
hepatic impairment and use of medications in pregnancy. Internet sources of prescribing were used
by about half of the general practitioners asked. When used they were reasonably frequently utilised
People sources of prescribing information included pharmacists, GP colleagues, hospital- based and
private specialists. Pharmacists were used on a weekly and monthly basis for advice and felt to be of
high value. GP colleagues were also in the main, accessed on a weekly basis and felt to be very
useful. Forty two percent of GPs without broadband in their office were considered to be
recommended practice (best practice) prescribers and 58% of GPs with broadband were considered
other prescribers. For finding information on Chloroquine resistant malaria 46% used Text sources,
22% used websites, 20% used Govt agencies and 11% used colleague contacts.
MIMs is a commonly used source but needs broadening to include more information on renal/liver
dysfunction etc. Prescribers following recommended practice were more likely to have broadband
internet available. Information about Malaria and other travel issues is probably best dealt with using
internet sites and broadband would help in this aspect. Encouraging GPs to use the free British
National Formulary could also facilitate quality practice.
Health for kids asthma management: adapting the best available guidelines to ensure the best possible care
Speaker: Tari Turner, Centre for Clinical Effectiveness, Monash Institute of Health Services Research,
‘Health for Kids in the South East’ is a Victorian Government funded project designed to improve
health care for children through best practice and partnerships. A major aspect of the project is the
development of evidence-based practice guidelines for common conditions.
The aim was to pilot an evidence-based process for guideline development by adapting existing high
quality asthma guidelines for local use by a tertiary paediatric hospital, local GPs and community
We searched for existing evidence for developing evidence-based guidelines and distilled an
evidence-based process for guideline development. We formed a multidisciplinary guideline
development group (GDG) which included hospital staff, consumers and general practitioners.
Existing guidelines were identified and appraised, then adapted to create a locally appropriate
evidence-based practice guideline for the management of asthma in children.
We identified two guidelines, the British Thoracic Society Guideline on the Management of Asthma
and the Royal Children’s Hospital Melbourne Asthma Best Practice Guidelines, as representing the
best in evidence-based management and the best in local consensus management of asthma,
respectively. Adaptation involved further literature searches, changes to medications and dosing to
reflect differing availability of drugs in Australia, removal of sections pertaining only to adult asthma,
and changes of emphasis in consensus based recommendations. Although the changes to the
content (and particularly the recommendations) were relatively minor, the GDG made substantial
changes to the format and language to reflect local practice.
Adapting existing high quality evidence-based guidelines is an appropriate, efficient way of creating
local guidelines. Adaptation may involve substantial changes to layout and language, even if few
changes are made to the recommendations of the existing guidelines.
Quality in allied health care: where is the place for guidelines?
Speaker: Saravana Kumar, Centre for Allied Health Evidence, University of South Australia, Australia
The issue of quality has been of great concern in the health care system as we continue to witness
dramatic changes in the structure and delivery of care.
Unlike, the medical profession, the ‘quality movement’ in allied health is in its infancy. Allied health
professions, including Physiotherapy, routinely are now faced with issues of accountability and
justification of care as part of the quality service delivery. As part of this process, increasingly, all
stakeholders of allied health (providers, patients, and funders) are relying on evidence-based practice
and clinical guidelines to help guide the process of quality service delivery.
2nd Guidelines International Network Conference, 1–3 November 2004
Usable guidelines: supporting the diversity of general practice
Speaker: Elizabeth Deveny, Therapeutic Guidelines Limited, Australia
Prescribing is one of the research domains where most work has been undertaken on developing
clinical decision support software. It is also one of the areas where Australian General Practitioners
(GPs) have been most active in computerising their clinical work. The practice of prescribing, with its
lists of drugs and the possibilities of events such as drug–drug interactions offers opportunities for
utilising computers. More generally, evidence-based approaches to practice encourage clinicians to
access current clinical evidence in order to provide the best quality of care. Quality Use of Medicines
initiatives, medical informatics literature and many organisations concerned with ‘quality of health
care’ regularly argue that electronic decision support, based on well-evidenced clinical practice
guidelines (CPGs) and embedded in clinicians’ computers, will improve the quality and
appropriateness of prescribing. This improvement is, in turn, claimed to result in better patient
outcomes, in particular by promoting best practice and reducing adverse events.
The overall aim of the research project was to identify how clinicians determine their needs for
information when making clinical decisions. It explored whether clinicians needed (and wanted)
technological, or other, assistance with decision-making. In doing so, it also paid particular attention to
the attitudes of clinicians towards computer use during consultations. This paper describes some
computer interactions between GPs during consultations. It uses transcript and observational data
from GP interviews and observations to re-construct computer-clinician interactions with CPGs. In
doing so, it illustrates how translating guidelines into an electronic format may shape clinical practice,
as well as GP-patient interactions, during consultations.
Evidence-based information for health practitioners: dilemmas and solutions from an Australian perspective
Speaker: Karen Luxford, on behalf of Katherine Vaughan, National Breast Cancer Centre (NBCC), Additional Authors: Alison Evans; Karen Luxford; Elmer Villanueva; and Helen Zorbas
The NBCC has been a leader in Australian Clinical Practice Guidelines (CPGs), developing and
implementing nine comprehensive sets of breast and ovarian cancer-related CPGs since its
establishment in 1995. However, as experienced by other CPG developers, development and
updating of CPGs has been slow and resource intensive, each taking about three years to complete,
including peer-review and endorsement by the Australian government. These comprehensive, paper-
based CPGs quickly become out-of-date in areas with rapidly emerging evidence. The NBCC shares
challenges faced by other information providers in supplying stakeholders with up-to-date evidence-
based information in a timely and cost-effective manner.
The aim was to explore approaches to ensuring Australian health practitioners are kept up-to-date
about evidence impacting on clinical practice in breast and ovarian cancer within budgetary
Approaches employed by local and international organisations to develop, update and disseminate
evidence-based information were examined. These widely varying approaches were used to inform
an NBCC strategy for maintaining the currency of evidence-based information for health practitioners.
2nd Guidelines International Network Conference, 1–3 November 2004
As no single approach appeared to be more effective or used more frequently than any other, the
NBCC developed a strategy to pilot a range of approaches, including: • a move from complete, paper-
based sets of CPGs to searchable, topic-specific web-based CPGs • prioritisation of topics for
systematic ongoing surveillance • alternative methods of CPG endorsement • alternative avenues for
publishing CPG updates, such as supplements to clinical journals and the NBCC website •
dissemination of key emerging clinical evidence directly to health practitioners via e-alerts and fax-
New approaches are required to ensure evidence-based information is developed and updated in a
timely manner within budgetary constraints. Ongoing lessons learned will have broad implications for
CPG development, dissemination and implementation.
An international survey of guideline developers' patient involvement methodologies.
Speaker: Sara Twaddle, on behalf of Joanne Topalian; SIGN, United Kingdom Additional Author: Claudia Pagliari, University of Edinburgh, United Kingdom
In March 2002, the first author performed an email survey of 15 members of the AGREE
1) to establish which of the organisations were involving patients, carers or patient representatives in
2) to assess what techniques were employed by those organisations that did involve patients, carers
3) to find out what plans these organisations had for involving patients, carers and/or patients'
Eight responses were received and a very mixed picture of international patient involvement in
guideline development emerged. Five of the respondents involved patients or carers or patients'
representatives in their guideline development processes. The level of involvement varied between
those that included such representatives as members of guideline groups (three organisations) to
those that included patient organisations when inviting comments on draft guidelines.
2.5 years have passed since this small-scale survey. Patient involvement in all aspects of health care
continues to be a dominant policy theme in many parts of the world yet there is little consensus on
appropriate methods of consumer inclusion in guideline development. The emergence of the GIN
network represents an ideal opportunity to build upon the above pilot study to explore the prevalence
and nature of patient involvement practices in member states. A mixed format survey will explore the
ways in which patients are identified, recruited, trained and utilised in the process of guideline
development and examine common barriers and facilitators to consumer involvement.
The objective was to establish a base line picture of the nature of patient involvement activities in
clinical guideline development across the world. This should facilitate shared learning between
member organisations, reduce duplication of effort, guide best practice and aid the development of an
agreed methodology for patient involvement
2nd Guidelines International Network Conference, 1–3 November 2004
The survey instrument will be developed and piloted on five international guideline development
colleagues. Following any amendments, it will be distributed to the GIN Coordinator who will email it
directly to the Lead at each of the member organisations.
The anonymised results and recommendations based on them will be summarised and published on
the GIN and SIGN websites and the research will be published in the scientific literature. A workshop
for GIN members to explore the implications of the results will be held and this may be followed by a
further exercise to develop consensus-based guidelines on patient involvement.
We ask that the members of GIN please assist us by responding swiftly to the email survey, due for
Ibero-American guidelines: useful resource or unnecessary workload in the German Guideline Clearinghouse (GGC) process?
Speaker: Christian Thomeczek, Heinrich-Heine University, Gernany Additonal Authors: Elizabeth Bandeira-Echtler, O Weingart; B Richter, H Kirchner, C Thomeczek and G Ollenschläger; Heinrich-Heine University, Germany
The GGC was established at the Agency for Quality in Medicine in 1999 in order to assure and
improve the quality of clinical practice guidelines. GGC’s evaluation focuses on the English and
German languages (EGL). Little is known about the quality and methodology of guidelines being
established in other regions, such as the Ibero-American language (IAL) area.
The objective was to find out whether IAL guidelines should be included in future GGC evidence-
An adapted GGC systematic literature search published between 1990 and 2003 was performed in
medical databases (Medline, LILACS), special guideline databases (leitlinien.de, ngc.gov, g-i-n.net)
and the Internet (Google). Inclusion criteria: Diabetes mellitus type 2; Spanish or Portuguese
language; newest version of guideline. The methodological appraisal was performed by using the
GGC checklist (version 2000) comparing IAL with EGL guidelines, the latter being appraised in the
730 IAL references were tracked down. According to inclusion criteria 10 IAL guidelines were
compared to 16 EGL guidelines. Main outcomes: The mean methodology scores concerning guideline
development, content, practicability and total sum for EGL guidelines did not show statistically
significant differences compared to IAL guidelines. Description of selection methods for identification
of evidence was reported in 19% of EGL and 40% of IAL guidelines.
No relevant methodological differences could be detected between IAL and EGL type 2 diabetes
mellitus guidelines. It appears to be useful for future GGC projects to include guidelines from the IAL
area. A pilot study should be initiated to investigate the influence of the inclusion of IAL guidelines on
the quality and results of the GGC practice. Theoretical socio-cultural differences could be elucidated
2nd Guidelines International Network Conference, 1–3 November 2004
Trial and Error: The Supreme Court’s Philosophy of Science Frye in excluding the plaintiffs’ experts’ testi-Apparently equating the question of whether expert testimony is reliable withthe question of whether it is genuinely scientific, in Daubert v Merrell Dow Phar-maceuticals, Inc (1993) the US Supreme Court ran together Karl Popper’s anddectin was teratogenic. So the Supreme Cour
id2377015 pdfMachine by Broadgun Software - a great PDF writer! - a great PDF creator! - http://www.pdfmachine.com http://www.broadgun.com Chenopodium ambrosioides (Chenopodiaceae) (Syn.: Teloxys ambrosioides, Atriplex ambrosioides) English: Skunkweed, Mexican tea, epazote, Westindian goosefoot, hedge mustard, Jerusalem parsley, sweet pigweed, wormseed French: Epazote, The du Mexique