Evidence-Based Treatments (EBTs) for Depression What are Evidence-Based Treatments (EBT)?
• EBTs apply the best available evidence gained from scientific
research to decision-making about treatment.
• EBTs are shown in randomized clinical trials to be effective in
reducing symptoms of a particular disorder and/or improving functioning
Types of EBTs for Depression Cognitive Behavior Therapy (CBT)
Brief, structured treatment that focuses on the relationship
Maladaptive cognitive styles are identified and more realistic and
Behavioral change such as engagement in mood elevating activities is
Also includes relaxation, problem solving and goal setting Therapist-as-coach model
Mindfulness-based CBT
Derived from a mindfulness-based stress reduction program with
the primary goal of preventing depression relapse.
Combines mindfulness techniques with aspects of cognitive therapy Mindfulness techniques include bringing attention to the present
experience, focusing on the breath, detaching from negative thoughts, accepting difficulties, and cultivating self-compassion.
Family Talk Preventive Intervention
This was written by Beardslee WR, Martin JL, and Gladstone TR (copyright 2009). This work was funded by the National Institute of Mental Health, the Sidney J. Baer, Jr. Foundation, and the William T. Grant Foundation. Supporting institutions include the Department of Psychiatry, Children's Hospital Boston and the Judge Baker Children's Center.
Module 2 Handout
Includes a plan for strategies to use when relapse is suspected
Module 2 Handout
Evidence-Based Treatments (EBTs) for Depression Con’d Interpersonal therapy (IPT)
Brief, structured treatment that focuses on interpersonal problems commonly experienced by depressed individuals. Involves decreasing an individual’s psychosocial problems through education and practice Central goals are improving interpersonal interactions and communications
Pharmacological Therapy
A physiological effect of depression is to decrease available neurotransmitters, or chemical messengers, in the brain, especially serotonin, acetylcholine and norepinephrine Medications help to increase the availability of these neurotransmitters to more typical levels Medications include:
-Selective Serotonin Reuptake Inhibitors, e.g., Fluoxetine (Prozac), Paroxetine (Paxil), Sertraline (Zoloft) -Norepinephrine Selective Reuptake Inhibitors, e.g., Reboxetine (Vestra), Desipramine (Norpramin, Pertofrane) -Serotonin-Norepinephrine Reuptake Inhibitors, e.g., Venlafaxine (Effexor) -Tricyclic Antidepressants, Amitriptyline (Elavil), Imipramine (Janimine, Tofranil), Trimipramine (Surmontil) TCA
Examples of non-pharmacological options include omega 3 fatty acids
The Depression reading list handout lists helpful websites and books to learn more about pharmacological and non-pharmacological treatments for depression. For exampl
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