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Monoclonal Antibody to TNF-alpha
Purified Antibody (0.025 mg)
Isotype:
Specificity:
The mouse monoclonal antibody MAb1 recognizes human 17-26 kDa cytokineTNF-alpha (tumor necrosis factor alpha).
Regulatory Status:
Immunogen:
Species Reactivity:
Application:
Western BlottingELISAApplication note:Can be used as capture antibody in combination with biotinylatedantibody MAb11.
Functional Applicationneutralization Purification:
Purified from cell culture supernatant by protein-A affinity chromatography.
Concentration:
Storage Buffer:
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 Storage / Stability:
Store at 2-8oC. Do not freeze. Do not use after expiration date stamped on viallabel.
Expiration:
Lot Number:
Background:
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NKcells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDafree molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stabletrimers, but also other multimeric complexes. In the immune system, it is animportant regulator, which has cytolytic and cytostatic activity against a range oftumor cells, increases fibroblast proliferation and supports neutrophil chemotaxisand phagocytosis.
For laboratory research only, not for drug, diagnostic or other use.
EXBIO Praha | Nad Safinou II 341 | 252 42 Vestec u Prahy | Czech RepublicTel: +420 261 090 666 | Fax: +420 261 090 660 | orders@exbio.cz | www.exbio.cz References:
*Ahlstedt I, Lindholm C, Lönroth H, Hamlet A, Svennerholm AM, Quiding-JärbrinkM: Role of local cytokines in increased gastric expression of the secretorycomponent in Helicobacter pylori infection. Infect Immun. 1999 Sep;67(9):4921-5.
*Lindholm C, Naylor A, Johansson EL, Quiding-Järbrink M: Mucosal vaccinationincreases endothelial expression of mucosal addressin cell adhesion molecule 1 inthe human gastrointestinal tract. Infect Immun. 2004 Feb;72(2):1004-9.
*Wahlström J, Katchar K, Wigzell H, Olerup O, Eklund A, Grunewald J: Analysis ofintracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis. AmJ Respir Crit Care Med. 2001 Jan;163(1):115-21.
*Yan SR, Qing G, Byers DM, Stadnyk AW, Al-Hertani W, Bortolussi R: Role ofMyD88 in diminished tumor necrosis factor alpha production by newbornmononuclear cells in response to lipopolysaccharide. Infect Immun. 2004Mar;72(3):1223-9.
*Visser J, Graffelman W, Blauw B, Haspels I, Lentjes E, de Kloet ER, NagelkerkenL: LPS-induced IL-10 production in whole blood cultures from chronic fatiguesyndrome patients is increased but supersensitive to inhibition by dexamethasone.
J Neuroimmunol. 2001 Oct 1;119(2):343-9.
*Cesaro-Tadic S, Dernick G, Juncker D, Buurman G, Kropshofer H, Michel B,Fattinger C, Delamarche E: High-sensitivity miniaturized immunoassays for tumornecrosis factor alpha using microfluidic systems. Lab Chip. 2004 Dec;4(6):563-9.
For laboratory research only, not for drug, diagnostic or other use.
EXBIO Praha | Nad Safinou II 341 | 252 42 Vestec u Prahy | Czech RepublicTel: +420 261 090 666 | Fax: +420 261 090 660 | orders@exbio.cz | www.exbio.cz

Source: http://www.exbio.cz/pdf/data_sheet_new.py/CLO000000000000505/1/18/datasheet-11-687-C025.pdf

Msctechsheet.indd

Metabolic Synergy™ Nutritional Support for Optimal Glucose, Insulin & Leptin LevelsTHIS INFORMATION IS PROVIDED FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS ONLY. THIS INFORMATION IS INTENDED FOR PHYSICIANS AND OTHER LICENSED HEALTH CARE PROVIDERS TO USE AS A BASIS FOR DETERMINING WHETHER OR NOT TO RECOMMEND THESE PRODUCTS TO THEIR PATIENTS. THIS MEDICAL AND SC

Pii: s0142-9612(01)00003-5

Hydrogels for combination delivery of antineoplastic agentsKamal H. Bouhadir , Eben Alsberg , David J. Mooney * Department of Biologic and Materials Sciences, University of Michigan, 3074 H.H. Dow Building, 2300 Hayward Street, Ann Arbor, MI 48109-2136, USA Department of Chemical Engineering, University of Michigan, 3074 H.H. Dow Building, 2300 Hayward Street, Ann Arbor, MI 48109-

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