Eye on Influenza
January 26, 2007
Volume 3, Issue 9
Orange County Health Care Agency, Epidemiology & Assessment, 1719 W. 17th St. Santa Ana, CA 92706, (714) 834-8180
Influenza activity has increased in Orange County. Consider influenza in your patients presenting with fever and/or respiratory symptoms. Several types of influenza testing are
available; see http://www.cdc.gov/flu/professionals/diagnosis/labprocedures.htm for more information.
• DHHS awards contracts totalling $132.5 million to three companies to develop H5N1 vaccines using
adjuvants: Because adjuvants can be used to boost the immune system’s response to a vaccine, the use of adjuvants may expand vaccine supplies during a pandemic. For more info, please visit: http://www.hhs.gov/news/press/2007pres/20070117a.html.
• Reduced susceptibility to oseltamivir (Tamiflu) in 2 H5N1 cases in Egypt: Two patients from the
same household were infected with an H5N1 strain that had “moderately reduced susceptibility” to Tamiflu. Because there is no evidence that Tamiflu-resistant strains are spreading in Egypt or elsewhere, Tamiflu is still recommended as the first-line drug for treatment of H5N1 infection. For more info: http://www.cidrap.umn.edu/cidrap/content/influenza/avianflu/news/jan1807tamiflu.html. For WHO guidelines on treatment and prophylaxis of H5N1, see http://www.who.int/csr/disease/avian_influenza/guidelines/pharmamanagement/en/index.html.
Reported Influenza Cases by Type
Orange County, 2006-2007 Influenza Season
• In the past 2 weeks, 38 new influenza
cases (32 A, 4 B & 2 A/B unspecified) were
reported. Of the 56 total this season; 46
unspecified. 41 (73%) were reported from
hospitals and 15 (27%) were from ILI sentinel sites. Of the 24 subtyped flu A
Number Reported Flu
influenza A viruses have been strain-typed
40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Disease Week and Month
Avian Influenza Update
California and USA
• Additional H5N1 avian outbreaks have been reported • California reported regional influenza
in Hungary, Japan, Thailand, and Vietnam.
activity during week 3. Nationally, 81.5% of
• 269 human H5N1 cases have been confirmed in
influenza detections were A; 18.5% were B.
Azerbaijan (8), Cambodia (6), China (22), Djibouti (1),
92% of subtyped A viruses were A (H1); 8%
Egypt (19)*, Indonesia (80)*, Iraq (3), Thailand (25),
Turkey (12), and Vietnam (93), and have resulted in
163 (61%) deaths. H5N1-infected birds have been
Caledonia/20/99-like.** Both A (H3) viruses
reported in multiple areas in Asia, Africa and
Europe. For a list of H5N1-affected countries, see
like.** Of B viruses characterized, 67% were
*New reported case(s) since January 12nd.
B/Yamagata lineage. 52% of the B/Victoria
• Please contact OC Epidemiology immediately at 714-
834-8180 to report any suspect avian influenza cases.
**Components of the 2006-2007 US flu vaccine:
• A (H1N1): A/New Caledonia/20/99-like
• B: B/Malaysia/2506/2004-like (equal to
CDC: http://www.cdc.gov/flu/weekly/; HHS: http://www.pandemicflu.gov/
If you have any comments about the flyer, contact Pamela Roa Hipp or Alina Burgi at (714) 834-8180.
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Computerized Medical Imaging and GraphicsAtherosclerosis: The evolving role of vascular image analysisNational Technical University of Athens, School of Electrical and Computer Engineering, Biomedical Simulations and Imaging (BIOSIM) Laboratory,Iroon Polytechniou 9, Zografos 15780, Athens, GreeceAtherosclerosis, a chronic systemic degenerative disease involv-hemorrhage, large lipid cores,
Dear Parents, in the group/grade attended by your child head lice have been detected. Children affected will remain excluded from attending the institution until they represent no more danger of further circulation. Affection with head lice, however, has got nothing to do with wanting hygiene. Rather, it is caused by interpersonal contacts, mainly from “hair to hair“, especially in com