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Glaxo 2004-uk.doc

GlaxoSmithKline
Sector: Health care
Recommendation: BUY
Analyst: Casper Runge Albæk Tel. +45 89223700
E-mail: casper.albaek@jyskebank.dk
GlaxoSmithKline takes an optimistic view of 2005
GlaxoSmithKline
GlaxoSmithKline released its 2004 accounts – a year that was quite released reasonable
demanding. We took special note of the following: accounts for 2004
• sales and earnings were a shade below consensus; • the margins came under pressure due to rising costs; • expectations of 2005 are better than expected. In general, the accounts do not prompt us to change our recommendation of GlaxoSmithKline. On this background, we reiterate our BUY Sales and earnings a tad In 2004 GlaxoSmithKline generated sales of GBP 20.4bn, whereas sales of
below consensus
GBP 20.5bn had been expected. This resulted in EPS of 75 pence, which was 0.5 pence below the consensus estimate. Sales – a mixed bag
The slightly sluggish sales in 2004 cannot be attributed to one single product, but cover a string of minor disappointments. It is, however, worth mentioning that sales of the diabetes drug Avandia/Avandamet, the cancer drug Zofran and the antidepressant Seroxat/Paxil were below expectations. The good news was, however, that the respiratory products, particularly Seretide/Advair, sold better than expected. It should be noted that this development took place despite the introduction of the mandatory discount in Germany and the inventory reductions in Italy. Thus Seretide/Advair is still an important factor in GlaxoSmithKline’s growth efforts. Incidentally, the company expects that sales will benefit further from the publication next month of the CONCEPT studies that compare Seretide with AstraZeneca’s Symbicort. Margin under pressure
Even though increasing production and R&D costs had been expected, these items in the accounts nevertheless offered negative surprises, which resulted in the somewhat disappointing EPS. Positive expectations of
One of the most positive aspects of the annual accounts was the company’s EPS growth forecast for 2005. GlaxoSmithKline expects high single-digit growth, which is presumably above the consensus estimate of growth just below 7%. We maintain our positive The accounts do not prompt us to change our BUY recommendation of
view of the share
GlaxoSmithKline. The company has come through a most demanding 2004 and now it embarking upon a period when we expect new product launches and applications for approval of products will have a favourable The analysis is based on information which Jyske Bank finds reliable, but Jyske Bank does not assume any responsibility for the correctness of the material nor for transactions made on the basis of the information or the estimates of the analysis. The estimates and recommendations of the analysis may be changed without notice. The analysis is for the personal use of Jyske Bank's customers and may not be copied. Translated by

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Add-on clinical effects of selective antagonist of5HT6 receptors AVN-211 (CD-008-0173) in patientswith schizophrenia stabilized on antipsychotic1 Laboratory of Psychopharmacology, National Center of Mental Health, Russian Academy of Medical Science, Moscow, Russia3 Avineuro Pharmaceuticals Inc., San Diego, California, USA4 Chemical Diversity Research Institute, Khimki, Moscov Region, RussiaT

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