Dr. Daniel R. Jones
Division of Natural Sciences and Mathematics
4201 South Washington Street Marion, IN 46953 Telephone: 765-677-2296 Fax: 765-677-2455 E-mail: [email protected]
9389 Rockwood Court, Noblesville, IN 46060
PERSONAL:
CAREER SUMMARY:
I have been blessed with opportunities to learn and serve in the dental as well as biomedical research and teaching fields. I am most grateful for the opportunity to serve Christ at Indiana Wesleyan University, integrating my faith with my work in the biomedical
EDUCATION/POSITIONS: 1984
D.D.S., Indiana University School of Dentistry
Ph.D., Biomedical Science, Wright State University
Post-doctoral Research Fellow, Eli Lilly and Company
Post-doctoral Research Scientist, Indiana University School of
Medicine/Indiana University School of Dentistry
Assistant Professor of Biology and Biochemistry, Indiana
Associate Professor of Biology and Biochemistry, Indiana
HONORS AND AWARDS: 2006
Gallup Organization Strengths-Based Curriculum Implementation
SCIENTIFIC PRESENTATIONS: 2006
Poster presentation, “CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay” Indiana Academy of Science Fall Meeting, Ball State University, Muncie, Indiana
John Wesley Honors College Faculty Lecture Series, oral presentation, “A Bare Bones Update on Osteoporosis Research at IWU.”
Poster presentation, “CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay,” Federation of American Societies for Experimental Biology Meeting, San Diego, California.
MENTORED SCIENTIFIC PRESENTATIONS: 2004
“Optimization of an Apoptosis Assay for Osteoblasts,” IWU Celebration of Scholarship, Mr. Kyle Anderson
“Apoptosis in Osteoblasts: Investigating a Potential Treatment for Osteoporosis,” IWU Celebration of Scholarship, Miss Jolie Hoffman, Mr. Kyle Anderson, Miss Amber Jones
Mentored the following 4th Annual IWU Celebration of Scholarship presentations:
“Osteoblast Apoptosis Inducers: A Factor in Osteoporosis,” Carolyn Bainbridge
“Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis,” Chana Hunter
“CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay,” Amber Jones
“TGF-β1 Levels in Dexamethasone-Induced Apoptotic Cells,” Chris Rose
“Apoptosis Detection Through DNA Fragmentation,” Michelle Stuttle
“Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling,” Brittany Wilkerson
“DNA Isolation of Black-Capped, Carolina, and Hybrid Chickadee Blood,” Jerica Derr
Mentored the following poster presentation at the Butler University Undergraduate Research Conference:
“CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay,” Amber Jones
Mentored the following poster presentations at the Indiana Academy of Science Fall Meeting:
“Successful Use of Guava Technologies’ Nexin Assay for Apoptosis Determination in MC3T3-E1 Cells,” Carolyn R. Bainbridge
“Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling,” Brittany N. Wilkerson
“Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis,” Chana N. Hunter
“TGF-β1 Levels in Dexamethasone-Induced Apoptotic MC3T3-E1 Cells,” Christopher T. Rose
“Genomic DNA Isolation from Indiana Chickadee Species (Poecilesp.),” Jerica N. Derr, Adam R. Thada
Mentored the following 5th Annual IWU Celebration of Scholarship presentations:
“Successful Use of Guava Technologies’ Nexin Assay for Apoptosis Determination in MC3T3-E1 Cells,” Carolyn R. Bainbridge
“Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling,” Brittany N. Wilkerson
“Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis,” Chana N. Hunter
“TGF-β1 Levels in Dexamethasone-Induced Apoptotic MC3T3-E1 Cells,” Christopher T. Rose
“Genomic DNA Isolation from Indiana Chickadee Species (Poecilesp.),” Jerica N. Derr, Adam R. Thada
Mentored the following presentations at the Indiana Academy of Science Fall Meeting:
“The Role of Protein Kinase B in CD40 Ligand-Mediated Prevention of Glucocorticoid-Induced Osteoblast Apoptosis,” Chika Nwulu
“A Preliminary Analysis of Nucleotide Differences Among Indiana Chickadee Species (Poecilesp.) at the Mitochondrial Cytochrome B Gene Locus,” Brett Bishop
“Development of a Non-Radioisotopic Southern Blot Technique for Detecting Restriction Fragment Length Polymorphisms Among Indiana Chickadee Species (Poecilesp.) and Their Hybrids at the C7 Homology Locus,” Matt Zuellig
Mentored the following 6th Annual IWU Celebration of Scholarship presentations:
“A Preliminary Analysis of Nucleotide Differences Among Indiana Chickadee Species (Poecilesp.) at the Mitochondrial Cytochrome B Gene Locus,” Brett Bishop
“Development of a Non-Radioisotopic Southern Blot Technique Detecting Restriction Fragment Length Polymorphisms Among
Indiana Chickadee Species and Their Hybrids at the Mitochondrial Cytochrome B Locus,” Matt Zuellig
“The Role of TGF-β1 in Osteoblasts in Glucocorticoid-Induced Osteoporosis,” Kristen Shafer
“Apoptosis in Osteoblasts Treated with Dexamethasone and CD40 Ligand,” Bethany Kline
“The Role of Protein Kinase B in CD40 Ligand-Mediated Prevention of Glucocorticoid-Induced Osteoblast Apoptosis,” Chika Nwulu
“Dexamethasone-Induced Apoptosis can be Detected in MC3T3-E1 Mouse Osteoblasts using Promega Corporation’s Caspase-3 Activity Assay,” Dan Seitz
“Effects of Estrogen on Osteoclast Apoptosis,” Chris Sloan and Laura Tedeschi
Mentored the following 7th Annual Celebration of Scholarship presentations:
“An Investigation of the In Vitro Induction of Osteoclast Apoptosis
Related to the Treatment of Osteoporosis by Estrogen,
Reveromycin A, and Orientin,” Laura Tedeschi
“Apoptosis in Osteoblasts Treated with Dexamethasone and CD40
“NF-κB Inhibition and Osteoporosis,” Brittany Mead
“The Role of Bcl-xL in the Apoptosis of Osteoblasts and
“The Validity of TRAP Staining for Interpreting Differentiation of
RAW264.7 Cells by RANKL,” Josh Pattengale
“The Signal Transduction Pathway of Tumor Necrosis Factor α-
as it Relates to Osteoclastogenesis,” Jordan Mast
Mentored the following presentation at the 125th Annual Indiana
“Preliminary Investigation of Apoptosis Induction in Osteoclasts by
the Flavonoid, Glucoluteolin,” Heather Morgan
PROFESSIONAL MEMBERSHIP: 2003- TEACHING CONFERENCES AND WORKSHOPS: 1998
IWU Teaching Workshops—Introduction to Blackboard Technology, Writing World Changing Outcomes, and Teaching Tips
Indiana University School of Medicine Premedical Advisor’s Conference
IWU Teaching Workshop—Faculty Guide to Helping Emotionally Distressed Students
12th Annual Conference on Bioethics—Genetic & Reproductive Ethics: The Scientific Cutting Edge & The Everyday Healthcare Challenges
Taylor University’s Technology for Teaching Conference
IWU Teaching Workshops—Are You Getting the IDEA? and Mentoring
NACADA (National Academic Advising Association) Academic Advising Summer Institute
Taylor University’s Technology for Teaching Conference
ANIMAL RESEARCH EXPERIENCE: 1981-1984
Rat intraperitoneal injections, anesthesia/exsanguination followed
by surgical removal of salivary glands for summer undergraduate
research experiences, Isoproteronal-induced proline-rich salivary
protein characterization, Purdue University Biochemistry
Rat hepatectomies, Characterization of hepatic lipase inhibitor
PUBLICATIONS: Jones, D. and Leffak, M. A Negative Regulatory Element of the Human Apolipoprotein A1 Gene, published abstract, The FASEB Journal, April 19, 1994, 8(7):A1335. Jones, Daniel R. and Leffak, Michael. A Bifunctional Regulatory Element of the Human ApoA-1 Gene Responsive to a Distal Enhancer. DNA & Cell Biology, February 1999, 18(2):107-19. Jones, D., Schmidt, R., Pickard, T., and Eacho, P. Dose-dependent Repression of Hepatic Lipase Gene Transcription by 17 β-estradiol, published abstract, The FASEB Journal, May 11, 2000, 14(8):A1340. Jones, Daniel R., Schmidt, Robert J., Pickard, Richard T., Foxworthy, Patricia S., and Eacho, Patrick I. Estrogen Receptor-Mediated Repression of Human Hepatic Lipase Gene Transcription, Journal of Lipid Research, 2002, 43:383-391. Jones, D., Torrungruang, K., Selvamurugan, N., Partridge, N., and Bidwell, J. Nmp4, a Nuclear Matrix Transcription Factor, Contributes to MMP-13 Transcription in Osteoblasts and Fibroblasts, published abstract, Molecular Biology of the Cell, November 2001 Supplement, 12:496A. Bidwell, J., Torrungruang, K., Alvarez, M., Rhodes, S., Shah, R., Jones, D., Charoonpatrapong, K., Hock, J., and Watt, A. Involvement of the Nuclear Matrix in the Control of Skeletal Genes: The NMP1 (YY1), NMP2 (Cbfa1), and NMP4 (Nmp4/CIZ) Transcription Factors, Critical Reviews in Eukaryotic Gene Expression, 2001, 11(4):279-298.
Shah R., Alvarez M., Jones D. R., Torrungruang K., Watt A. J., Selvamurugan N., Partridge N. C., Quinn C. O., Pavalko F. M., Rhodes S. J., Bidwell J. P. Nmp4/CIZ Regulation of Matrix Metalloproteinase 13 (MMP-13) Response to Parathyroid Hormone in Osteoblasts, American Journal of Physiology— Endocrinology & Metabolism, 2004, 287:289-296. Jones, Daniel R. Biology 102 Lab Manual, August 2005. INVITED TEXT REVIEW/NATIONAL COMMITTEES: 2005
Chapter review of the genetics text, “The Logic of Genetics,” for Benjamin Cummings
Chapter review of the genetics text, “iGenetics,” 2nd edition, for Benjamin Cummings
American Chemical Society—2008 National Biochemistry Exam Committee
GRANTS: 2004
Successful senior researcher grant submission to Indiana Academy of Science for the project, “An Investigation of the Anti-apoptotic Mechanism of CD40 Ligand in Dexamethasone-induced Osteoblast Apoptosis”
Mentored four individual students’ Lilly Student Research Award applications through IWU, two successfully awarded
Successful full funding of a Lilly Faculty Scholarship grant application through IWU entitled ”A Study of the Mechanisms of Dexamethasone-Induced Apoptosis in Osteoblasts—An Important Piece in the Osteoporosis Puzzle”
Mentored three individual students’ Lilly Student Research Award research
Successful funding of Lilly Faculty Scholarship grant application for summer research stipend
Successful funding for a senior research scientist grant from the Indiana Academy of Science, “Characterization of the Effect of Glucoluteolin, a Flavonoid, on Estrogen-Induced Apoptosis in Osteoclasts”
Successful funding of Lilly Faculty Scholarship grant application for summer research stipend
COMMUNITY SERVICE: 2000-
Coordinated my students’ efforts on Operation Christmas Child in conjunction with Lakeview Wesleyan Church, Marion, IN
Push-pull and Set-up Team—Hamilton County Passion Play, “Behold the Lamb,” Noblesville, IN
Usher—Hamilton County Passion Play, “Behold the Lamb,” Noblesville, IN
2006, 2007 ACSI District Science Fair judge 2009
Hamilton County Good Samaritan’s Food Delivery Participant
UNIVERSITY SERVICE: 2003-
Natural Sciences and Mathematics Division mentor for Barry
Natural Sciences and Mathematics Division mentor for Elie Weisel Foundation Prize in Ethics Essay Contest candidates
Member of Indiana Wesleyan University Institutional Review Board
Faculty member of College of Arts and Sciences’ Academic Advising Committee
Chairman of College of Arts and Sciences’ Academic Advising Committee
IWU IACUC (Institutional Animal Care and Use Committee)
CHURCH: 2002-04 Grace Community Church, Noblesville, IN 2002-04
Community Group Bible Fellowship, Grace Community Church
2004- Member of Harbour Shores Church, Cicero, IN 2004- Ambassadors Adult Bible Study Fellowship 2004-05
2006- Pathway to Maturity Bible Studies, Harbour Shores Church 2008- 2009 Harbour Shores Church, Prayer in the Home Leader and Participant
The Journal of the Norwalk Aquarium Societyregulations, and species we may find. Whether you are interested in native fishes,just want to get out of the house, or simply From Up-front want to watch everyone splashing around inthe water, this can be an excellent way tospend a day. This trip will be held on the DEPfree fishing day in early June. Further detailshas already been working to
PROGESTERONE ENZYME IMMUNOASSAY TEST KIT Catalog Number: PS-1113 Enzyme Immunoassay for the PRINCIPLE OF THE TEST Quantitative Determination of Progesterone Concentration in The progesterone EIA is based on the principle of Human Serum competitive binding between progesterone in the test specimen and progesterone-HRP conjugate for a constant amount of rabbit anti-prog