Anapharm europe bioanalytical methods 2013 april
LIST OF BIOANALYTICAL METHODS
NEWLY DEVELOPED OR RECENTLY UPDATED METHODS
Bioanalytical
Compound
Calibration Range
Bioanalytical matrix
Carbidopa ; Levodopa
LC/MS/MS
2-75 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
5-250 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Budesonide
LC/MS/MS
5-1000 pg/mL
Human EDTA Plasma
Formoterol
LC/MS/MS
0.4-100 pg/mL
Human EDTA Plasma
0.2-20 ng/mL; 0.2-20 ng/mL; 0.1-10 ng/mL
Tiotropium
LC/MS/MS
0.5-100 pg/mL
Human EDTA Plasma
LIST OF BIOANALYTICAL METHODS
Bioanalytical
Compound
Calibration Range
Bioanalytical matrix
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Betahistine metabolite (2-pyridylacetic acid)
Bicalutamide ((R)-(-)Bicalutamide ; (S)-(+)
Bicalutamide (R-(-) Bicalutamide ; (S)-(+)
Bicalutamide (R-(-) Bicalutamide ; (S)-(+)
Budesonide
LC/MS/MS
5-1000 pg/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
2-75 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
2-100 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Carbidopa ; Levodopa
LC/MS/MS
5-250 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
5-300 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Chlorpheniramine (S-(+)-clorpheniramine ;
2-2000 ng/mL ; 2-600 ng/mL ; 1-400 ng/mL
Deflazacort metabolite (21-OH-Deflazacort)
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Donepezil ((+)-Donepezil ; (-)-Donepezil)
Donepezil ((+)-Donepezil ; (-)-Donepezil)
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Fluticasone
LC/MS/MS
2-250 pg/mL
Human EDTA Plasma
Fluvastatin ((+)-3R,5S-Fluvastatin ; (-) -3S, 5R-
Formoterol
LC/MS/MS
0.4-100 pg/mL
Human EDTA Plasma
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen)
Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen)
Lercanidipine ((-)-R-Lercanidipine ; (+)-S-
Linopristin ; Linopristin Metabolite (RPR
Linopristin ; Linopristin Metabolite (RPR
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Metamizol metabolite (4-methylaminoantipyrine)
Metoprolol ((+)-R-Metoprolol ; (-)-S-Metoprolol)
Morphine ; Morphine-3-beta-D-glucoronide ;
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Paliperidone ((-) Paliperidone ; (+) Paliperidone)
Pentoxyfiline ; Metabolite I ; Metabolite V
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Salmeterol
LC/MS/MS
2-250 pg/mL
Human EDTA Plasma
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Simvastatin ; b-Hydroxy Acid Simvastatin
Simvastatin ; b-Hydroxy Acid Simvastatin
∆9-Tetrahydrocannabinol; 11-Hydroxy-∆9-
0.2-20 ng/mL; 0.2-20 ng/mL; 0.1-10 ng/mL
Tiotropium
LC/MS/MS
0.5-100 pg/mL
Human EDTA Plasma
Tolterodine ; 5-hydroxymethyl Tolterodine
Tolterodine ; 5-hydroxymethyl Tolterodine
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
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Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
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Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636
[email protected] www.anapharmeurope.com
Source: http://www.anapharmeurope.com/pdf/Anapharm%20Europe%20Bioanalytical%20methods.pdf
WADA 2006 PROHIBITED LIST: A summary of the major changes Other minor amendments have been made to the 2006 List. Please consult the Summary of Modifications for 2006 and the 2006 Monitoring Program available on the WADA website. Gonadotrophins LH and hCG previously prohibited in males and females in the 2005 List are now only Glucocorticosteroids* All topical* pr
A Guide for Classroom – Stage 4 Oxford Reading Tree is the most popular reading programme in the UK, and used in approximately 14,000 primary schools. Its balanced approach, which provides a range of skills and strategies for reading, has proved highly successful at teaching children to read. Oxford Reading Tree is divided into stages. Stage 1 teaches children important pre-reading skil
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LIST OF BIOANALYTICAL METHODS 
Betahistine metabolite (2-pyridylacetic acid)
Bicalutamide ((R)-(-)Bicalutamide ; (S)-(+)
Bicalutamide (R-(-) Bicalutamide ; (S)-(+)
Bicalutamide (R-(-) Bicalutamide ; (S)-(+)
Budesonide 
Carbidopa ; Levodopa 
Donepezil ((+)-Donepezil ; (-)-Donepezil)
Donepezil ((+)-Donepezil ; (-)-Donepezil)
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Fluticasone 
Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen)
Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen)
Lercanidipine ((-)-R-Lercanidipine ; (+)-S-
Linopristin ; Linopristin Metabolite (RPR
Linopristin ; Linopristin Metabolite (RPR
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Metamizol metabolite (4-methylaminoantipyrine)
Metoprolol ((+)-R-Metoprolol ; (-)-S-Metoprolol)
Morphine ; Morphine-3-beta-D-glucoronide ;
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Paliperidone ((-) Paliperidone ; (+) Paliperidone)
Pentoxyfiline ; Metabolite I ; Metabolite V
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Salmeterol 
Simvastatin ; b-Hydroxy Acid Simvastatin
Simvastatin ; b-Hydroxy Acid Simvastatin
∆9-Tetrahydrocannabinol; 11-Hydroxy-∆9-
0.2-20 ng/mL; 0.2-20 ng/mL; 0.1-10 ng/mL
Tiotropium 
Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
Warfarin (R-(+) Warfarin ; S-(-)-Warfarin)
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